Collagen membrane and L-PRF with Xenogeneic bone block for vertical ridge augmentation: An Experimental study in a canine model
Eldabe, A., Gamal, A., Amr, A., Abdel Hamid, E., Abu-Seida, A. (2021). Collagen membrane and L-PRF with Xenogeneic bone block for vertical ridge augmentation: An Experimental study in a canine model. EKB Journal Management System, 22(2), 92-99. doi: 10.21608/asdj.2021.82124.1057
Abdelrahman khalaf Eldabe; Ahmad Gamal; Ahmed Elsayed Amr; Ehab Saeed Abdel Hamid; Ashraf Abu-Seida. "Collagen membrane and L-PRF with Xenogeneic bone block for vertical ridge augmentation: An Experimental study in a canine model". EKB Journal Management System, 22, 2, 2021, 92-99. doi: 10.21608/asdj.2021.82124.1057
Eldabe, A., Gamal, A., Amr, A., Abdel Hamid, E., Abu-Seida, A. (2021). 'Collagen membrane and L-PRF with Xenogeneic bone block for vertical ridge augmentation: An Experimental study in a canine model', EKB Journal Management System, 22(2), pp. 92-99. doi: 10.21608/asdj.2021.82124.1057
Eldabe, A., Gamal, A., Amr, A., Abdel Hamid, E., Abu-Seida, A. Collagen membrane and L-PRF with Xenogeneic bone block for vertical ridge augmentation: An Experimental study in a canine model. EKB Journal Management System, 2021; 22(2): 92-99. doi: 10.21608/asdj.2021.82124.1057

Collagen membrane and L-PRF with Xenogeneic bone block for vertical ridge augmentation: An Experimental study in a canine model

Ain Shams Dental Journal
Article 13, Volume 22, Issue 2, June 2021, Page 92-99  XML PDF (681.98 K)
Document Type: Original articles
DOI: 10.21608/asdj.2021.82124.1057
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Authors
Abdelrahman khalaf Eldabe email 1; Ahmad Gamal2; Ahmed Elsayed Amr3; Ehab Saeed Abdel Hamid4; Ashraf Abu-Seida5
1Department of Oral Medicine , Periodontology and Diagnosis , faculty of dentistry Assiut University, Assiut, Egypt
2Department of Oral Medicine, Periodontology, Faculty of Dentistry, 6 October University, Giza, Egypt
3Department of oral medicine and Periodontology, Faculty of Dentistry, Ain shams university, Cairo, Egypt
4Department of oral pathology, Faculty of Dentistry , Badr University, Egypt
5Dept. of Surgery, Anesthesiology and Radiology, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt
Abstract
Background: Guided bone regeneration has been tried using a variety of barrier membranes, and it is thought to be achieved when osteoprogenitor cells are allowed to repopulate the area of the bone defect . PRF, have the advantage that without anticoagulants, a fibrin matrix that incorporates the full set of growth factors trapped within its matrix can slowly release these growth factors over time. The aim of this study was to evaluate the benefits of using L-PRF in bone regeneration when utilizing GBR technique.
Methods: The study involved six mature mongrel dogs, each weighing at least 18 kg. In the first phase, four standardized saddle-type defects were prepared. After a two-month recuperation period, a xenogeneic block graft was utilized in the two groups. In group (1), block graft was covered by a collagen membrane (Block + C M), while in group (2), two L-PRF membranes were added first before top coverage by collagen membrane( Block + L PRF + C M ). Animals were subjected to surgical reentry after a three-month healing period following grafting for clinical observation and then euthanized for histological processing.
Results: In group 1, there was a statistically significant difference between (New bone apical side) and each of (New bone periosteum side) and (New bone intermediate) (p0.001).In group 2 no statistically significant difference between (New bone periosteum side), (New Bone intermediate) and (New Bone apical side) (p=0.225).
Conclusion:Tthe usage of the (L PRF ) in ridge augmentation appears to enhance the quality of regenerated bone.
Keywords
Ridge augmentation; leukocyte and platelet-rich fibrin; collagen membrane; tissue engineering
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