The antimicrobial effect of eugenol on lactobacilli isolated from children’s saliva compared to chlorhexidine (in-vitro study)
Salma, R., Matar, M., Darwish, S., Elseoudy, N., Kandil, M., Mehelba, M., Lotfy, W. (2022). The antimicrobial effect of eugenol on lactobacilli isolated from children’s saliva compared to chlorhexidine (in-vitro study). EKB Journal Management System, 68(2), 1141-1148. doi: 10.21608/edj.2022.110223.1900
Rehab Samir Salma; Moustafa A Matar; Sherif S Darwish; Nader A. Elseoudy; Moustafa A. Kandil; Mohab H. Mehelba; Walid A Lotfy. "The antimicrobial effect of eugenol on lactobacilli isolated from children’s saliva compared to chlorhexidine (in-vitro study)". EKB Journal Management System, 68, 2, 2022, 1141-1148. doi: 10.21608/edj.2022.110223.1900
Salma, R., Matar, M., Darwish, S., Elseoudy, N., Kandil, M., Mehelba, M., Lotfy, W. (2022). 'The antimicrobial effect of eugenol on lactobacilli isolated from children’s saliva compared to chlorhexidine (in-vitro study)', EKB Journal Management System, 68(2), pp. 1141-1148. doi: 10.21608/edj.2022.110223.1900
Salma, R., Matar, M., Darwish, S., Elseoudy, N., Kandil, M., Mehelba, M., Lotfy, W. The antimicrobial effect of eugenol on lactobacilli isolated from children’s saliva compared to chlorhexidine (in-vitro study). EKB Journal Management System, 2022; 68(2): 1141-1148. doi: 10.21608/edj.2022.110223.1900

The antimicrobial effect of eugenol on lactobacilli isolated from children’s saliva compared to chlorhexidine (in-vitro study)

Egyptian Dental Journal
Article 2, Volume 68, Issue 2 - Serial Number 1, April 2022, Page 1141-1148  XML PDF (592.65 K)
Document Type: Original Article
DOI: 10.21608/edj.2022.110223.1900
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Authors
Rehab Samir Salma email orcid 1; Moustafa A Matarorcid 1; Sherif S Darwishorcid 1; Nader A. Elseoudy2; Moustafa A. Kandil2; Mohab H. Mehelba2; Walid A Lotfyorcid 3
1Department of Pediatric Dentistry, Faculty of Dentistry, Pharos University in Alexandria, Alexandria, Egypt.
2Senior Student, Faculty of Dentistry, Pharos University in Alexandria, Alexandria, Egypt.
3Department of Microbiology, Faculty of Dentistry, Pharos University in Alexandria, Alexandria, Egypt
Abstract
Background: Eugenol is a frequent component of dental biomaterials and is known to exhibit a range of antimicrobial activity. However, there is a lack of reports on evaluating the antimicrobial activity of eugenol versus chlorhexidine on oral lactobacilli. Material and methods: In the current study, we evaluated the in vitro antimicrobial activity of eugenol by agar diffusion method on 15 Lactobacillus isolates initially isolated from pre-school children and compared the efficacy of eugenol with chlorhexidine. Results: the study showed inhibition zones of eugenol ranged from 6 to 10 mm, while those of chlorhexidine ranged from 7 to 11mm. The statistical analysis using paired t-test revealed a significant difference (P < 0.001) for eugenol and chlorhexidine groups with respect to their antimicrobial efficacy against oral lactobacilli. The minimum inhibitory concentration of eugenol and chlorhexidine were 100-400 and 20-40 micro gm/ml, respectively. Conclusion: The effectiveness of eugenol against lactobacilli was promising in inhibiting caries
Keywords
Antimicrobial; Chlorhexidine; Early childhood caries; Eugenol; Lactobacilli
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