Antibiotic resistance pattern of Salmonella species isolated from Typhoid patients in Jigawa state, Nigeria
U., A., M., Y., A. D., U., S.K., A. (2020). Antibiotic resistance pattern of Salmonella species isolated from Typhoid patients in Jigawa state, Nigeria. EKB Journal Management System, 4(2), 696-703. doi: 10.21608/nrmj.2020.84018
Adamu U.; Yusha’u M.; Usman A. D.; Abdulhadi S.K.. "Antibiotic resistance pattern of Salmonella species isolated from Typhoid patients in Jigawa state, Nigeria". EKB Journal Management System, 4, 2, 2020, 696-703. doi: 10.21608/nrmj.2020.84018
U., A., M., Y., A. D., U., S.K., A. (2020). 'Antibiotic resistance pattern of Salmonella species isolated from Typhoid patients in Jigawa state, Nigeria', EKB Journal Management System, 4(2), pp. 696-703. doi: 10.21608/nrmj.2020.84018
U., A., M., Y., A. D., U., S.K., A. Antibiotic resistance pattern of Salmonella species isolated from Typhoid patients in Jigawa state, Nigeria. EKB Journal Management System, 2020; 4(2): 696-703. doi: 10.21608/nrmj.2020.84018

Antibiotic resistance pattern of Salmonella species isolated from Typhoid patients in Jigawa state, Nigeria

Novel Research in Microbiology Journal
Volume 4, Issue 2, March and April 2020, Page 696-703  XML PDF (299.98 K)
Document Type: Original Article
DOI: 10.21608/nrmj.2020.84018
View on SCiNiTO View on SCiNiTO
Authors
Adamu U. email orcid 1; Yusha’u M.2; Usman A. D.2; Abdulhadi S.K.3
1Medical Laboratory Department, Hadejia General Hospital, Jigawa, Nigeria
2Department of Microbiology, Bayero University, P.M.B. 3011, Kano, Nigeria
3Department of Medical Laboratory Science, Bayero University, P.M.B. 3011, Kano, Nigeria
Abstract
This study was designed to determine the antibiotic resistance pattern of Salmonella spp. isolated from clinical samples of symptomatic and asymptomatic typhoid patients, selected from some hospitals in Jigawa State, Nigeria. Four hundred bacterial isolates were recovered from these samples, were identified as; Salmonella typhimurium, S. enteritidis, S. typhi, S. paratyphi A, and S. paratyphi B using microgen biochemical system, according to the standard techniques. The antibiogram of all these Salmonella spp. were carried out using standard oxoid disc of different antibiotics. Double disc diffusion technique was employed to determine the isolates’ capacity to produce β-lactamase. Results showed 5(1.25 %), 0(0.0 %), 0(0.0 %) of the samples collected were positive for extended spectrum β-lactamases (ESBL), AmpC β-lactamase, and Metallo β-lactamases (MBL), respectively. The antibiogram profile of the isolates showed that 100 % of these isolates are susceptible to Imipenem, only 3 % exhibited resistance to ceftriaxone, whereas 7 % demonstrated resistance to ciprofloxacin. To the best of our knowledge, this the first study of this kind in the Jigawa state, especially on these Salmonella spp. The study concluded that β-lactamases with the capacity of conferring multidrug resistance were recorded in Salmonella spp. isolated from patients in several hospitals of Jigawa State, Nigeria. 
Keywords
Antibiotics; ESBL; Resistance; Salmonella spp
Statistics
Article View: 174
PDF Download: 115