Serum Mannose Receptor as a Diagnostic Bio-Marker for Sepsis in ICU Patients in Ain Shams University Hospitals | ||||
| Egyptian Journal of Medical Microbiology | ||||
| Article 6, Volume 31, Issue 2, April 2022, Page 29-36 PDF (574.73 K) | ||||
| Document Type: New and original researches in the field of Microbiology. | ||||
| DOI: 10.21608/ejmm.2022.228620 | ||||
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| Authors | ||||
Fatma Mohamady Shehata  1; Taghreed Hamed El-khashab2; Fager Fathy Hussein2; Yasmin Mohamed Ahmed 3
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| 1Microbiology & Immunology, Faculty of medicine, Helwan University , Cairo, Egypt. | ||||
| 2Microbiology & Immunology, Faculty of medicine, Ain shams university, Cairo, Egypt. | ||||
| 3Microbiology &Immunology, Faculty of medicine, Ain shams university, Cairo, Egypt. | ||||
| Abstract | ||||
| Background: Sepsis is one of commonest complications that is associated with extended hospital stays. Making an early diagnosis is critical for improving its prognosis. Serum Mannose Receptor (sMR) is a biological biomarker which can be used in early diagnosis of sepsis. Objective: To investigate the value of sMR as a diagnostic biomarker for sepsis. Methodology: This study included 65 patients and 25 healthy individuals as control group. The patients’ group was divided into two groups according to SIRS criteria. Blood samples from patients were collected for blood cultures. sMR levels were measured in patients and control groups. Results: The commonest isolated organism by blood culture was S. aureus. SMR levels among cases in the both groups were higher than controls with statistically significant difference. SMR could be used to discriminate cases in both groups with 97.5% sensitivity, 80.0% specificity. Conclusion: sMR is a promising biomarker in early predictor of sepsis. | ||||
| Keywords | ||||
| Sepsis; sMR | ||||
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