Bacterial Co-Infection Among Corona Virus Disease-19 Patients in Zagazig University Quarantine Intensive Care Units | ||||
| Zagazig University Medical Journal | ||||
| Article 32, Volume 28, Issue 5, September 2022, Page 1147-1155 PDF (503.28 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/zumj.2022.129209.2535 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Esam Albashir Ahmed  1; Saad Samra2; Mohammed Fawzy Mohammed2; Lamiaa Gaber Zake 2
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| 1Department of Chest diseases, Faculty of Medicine, Tripoli University, Libya | ||||
| 2Department of Chest diseases, Faculty of Medicine, Zagazig University, Egypt | ||||
| Abstract | ||||
| Background: COVID-19 has affected millions of people worldwide. To date, efforts made to develop antiviral strategies for the treatment of COVID-19 remain underway. Respiratory viral infections predispose to co-infections which lead to increased disease severity and mortality. This study aimed to determine COVID-19 bacterial co-infection incidence and assess the severity and outcome among patients in Zagazig University quarantine ICUs. Patients and methods: This prospective cohort study was carried out on moderate and severe COVID-19 patients admitted to Zagazig University quarantine intensive care units , full history taken ,complete physical examination and vital signs with laboratory investigations ,bacterial co-infection assessment (within 48 hrs of admission ) in form of persisting fever or leucocytosis (neutrophilia) and high procalcitonin with blood or sputum cultures, follow up the patients till discharge or death. Results: Among 180 studied COVID-19 patients there was 21.1% of them had bacterial co-infection while 78.9 % were without bacterial co-infection, there was 8.9% with positive blood cultures and 16.1 with positive sputum cultures. There was significantly higher percent of severity, CPAP need and death rate among patients with bacterial co-infection ,there was statistically significant difference regarding duration of ICU stay with higher median in COVID-19 without bacterial co-infection. Conclusion: The incidence of COVID-19 bacterial co-infection among patients in Zagazig University quarantine ICUs was 21.1% with Klebsiella organism the most causative organism and there was significantly higher percent of severity and death rate among COVID-19 patients with bacterial co-infection. | ||||
| Keywords | ||||
| Bacterial co-infection; COVID-19; Intensive care units | ||||
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