Efficacy of Different Modalities in Treatment of Different Types of Fungal Sinusitis
Aleem, M., Nashar, A., Ezzat, W., Al-Shahat, M. (2022). Efficacy of Different Modalities in Treatment of Different Types of Fungal Sinusitis. EKB Journal Management System, 23(23), 1-12. doi: 10.21608/ejentas.2022.46414.1427
Mohammed Aleem; Abdel Hamid Nashar; Waleed Ezzat; Mohammed Al-Shahat. "Efficacy of Different Modalities in Treatment of Different Types of Fungal Sinusitis". EKB Journal Management System, 23, 23, 2022, 1-12. doi: 10.21608/ejentas.2022.46414.1427
Aleem, M., Nashar, A., Ezzat, W., Al-Shahat, M. (2022). 'Efficacy of Different Modalities in Treatment of Different Types of Fungal Sinusitis', EKB Journal Management System, 23(23), pp. 1-12. doi: 10.21608/ejentas.2022.46414.1427
Aleem, M., Nashar, A., Ezzat, W., Al-Shahat, M. Efficacy of Different Modalities in Treatment of Different Types of Fungal Sinusitis. EKB Journal Management System, 2022; 23(23): 1-12. doi: 10.21608/ejentas.2022.46414.1427

Efficacy of Different Modalities in Treatment of Different Types of Fungal Sinusitis

Egyptian Journal of Ear, Nose, Throat and Allied Sciences
Article 42, Volume 23, Issue 23, January 2022, Page 1-12  XML PDF (1.02 MB)
Document Type: Review article
DOI: 10.21608/ejentas.2022.46414.1427
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Authors
Mohammed Aleem email 1; Abdel Hamid Nashar1; Waleed Ezzat1; Mohammed Al-Shahat2
1ORL department, Faculty of medicine, Ainshams unversity- Egypt
2Mataria Teaching Hospital- Cairo-Egypt
Abstract
Background: Fungal rhinosinusitis (FRS) includes a spectrum of disease processes that vary in clinical presentation, histologic appearances, and treatment options.
Objective: This systematic review was done to reach the effective and safe method in management of FRS.
Patients and Methods: Meta-analysis was performed in accordance to the recommendations of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). This study used the published articles (from Jan1985 to Jan2018) in treatment of FRS via search in several databases.
Results: Finally, forty-five studies were included in this study. Fifteen of them assessed the treatment of fungal ball (FB) using mainly the functional endoscopic sinus surgery (FESS) the success rate was 98.1%. Twenty included studies have evaluated the management of allergic fungal sinusitis (AFS) via FESS, Systemic steroids, Antifungals and immunotherapy. The results showed that FESS represents the first-line, followed by aggressive medical therapies, the recurrence rate after postoperative steroids was 20.6%, postoperative antifungals was 40% and after immunotherapy was 9.1%. Ten included studies considered the Invasive Fungal sinusitis. The results showed that the combination of systematic antifungal therapy and aggressive surgical debridement was the treatment of the choice.
Conclusion: FESS is the treatment of choice for FB. AFS treatment consists of surgical extirpation of the allergic mucin and followed by anti-fungal therapy, Immunotherapy, and corticosteroids. Treatment of invasive fungal sinusitis includes surgical resection of necrotic tissues, systemic antifungal therapy and reversal of immune dysfunction
Keywords
Allergic fungal rhinosinusitis; antifungal in AFS; aspergillus in FB; fungus ball rhinosinusitis; immunotherapy in AFS; invasive fungal rhinosinusitis
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