Updates on toxicology of Aluminum Phosphide and different management protocols | ||||
| Zagazig University Medical Journal | ||||
| Article 1, Volume 28, Issue 6, November 2022, Page 1176-1183 PDF (332.04 K) | ||||
| Document Type: Review Articles | ||||
| DOI: 10.21608/zumj.2022.125913.2491 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Mohamed Abd-Elfatah Abd-Allah 1; Ahmed Abdalla  1; Nedaa Ali Mohamed1; Mohamed Musad Rady1; Ahmed Abdelaty Farrag1; Kareem Ashraf Salama2; Gamal Abd El-Nasser Rakha1; Yara Elfakhrany3
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| 1Faculty of Medicine, Zagazig University | ||||
| 2Faculty of Medicine, Zagazig University | ||||
| 3Department of Forensic Medicine and Toxicolgy, Faculty of Medicine, Zagazig University | ||||
| Abstract | ||||
| Background: Aluminum phosphide (ALP) is a poisonous chemical used to fumigate stored grains. Despite its severe toxicity, there is no antidote and only supportive measures are used. Aluminum phosphide causes mitochondrial damage and oxidative stress. We want to clarify incidence of ALP-toxicity in Egypt and globally, its consequences on various organs, and therapy options. The medical community must be informed of the increased risk of ALP-toxicity and the additional consequences seen in new patients. We examined PubMed, Cochrane, and Scopus databases to search for all ALP-toxicity consequences and decide the best option to be taken in acute AIP-toxicity and its sequelae. Conclusion: The growing market availability of AIP makes it an easy option for self-harm or perhaps murder. Due to the absence of a precise antidote, affected people die quickly. It's important for the medical staff to be aware of the increasing danger of ALP-toxicity and the new complications observed in the new cases. | ||||
| Keywords | ||||
| Aluminum phosphide; mechanism of action investigations; prognosis; elimination | ||||
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