Congenital Hydrocephalus: A review of Pathophysiology, Risk Factors, Genetics, Clinical Picture and Associated Congenital Anomalies
Aboel-Azm, Y., Abdel-Kareem, R., Saber, A., Ahmed, H. (2023). Congenital Hydrocephalus: A review of Pathophysiology, Risk Factors, Genetics, Clinical Picture and Associated Congenital Anomalies. EKB Journal Management System, 29(2), 587-591. doi: 10.21608/zumj.2022.125990.2493
yosra Aboel-Azm; Reham Helmy Abdel-Kareem; Ahmed Salem Saber; Hala Mahmoud Ahmed. "Congenital Hydrocephalus: A review of Pathophysiology, Risk Factors, Genetics, Clinical Picture and Associated Congenital Anomalies". EKB Journal Management System, 29, 2, 2023, 587-591. doi: 10.21608/zumj.2022.125990.2493
Aboel-Azm, Y., Abdel-Kareem, R., Saber, A., Ahmed, H. (2023). 'Congenital Hydrocephalus: A review of Pathophysiology, Risk Factors, Genetics, Clinical Picture and Associated Congenital Anomalies', EKB Journal Management System, 29(2), pp. 587-591. doi: 10.21608/zumj.2022.125990.2493
Aboel-Azm, Y., Abdel-Kareem, R., Saber, A., Ahmed, H. Congenital Hydrocephalus: A review of Pathophysiology, Risk Factors, Genetics, Clinical Picture and Associated Congenital Anomalies. EKB Journal Management System, 2023; 29(2): 587-591. doi: 10.21608/zumj.2022.125990.2493

Congenital Hydrocephalus: A review of Pathophysiology, Risk Factors, Genetics, Clinical Picture and Associated Congenital Anomalies

Zagazig University Medical Journal
Article 25, Volume 29, Issue 2, March 2023, Page 587-591  XML PDF (269.23 K)
Document Type: Review Articles
DOI: 10.21608/zumj.2022.125990.2493
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Authors
yosra Aboel-Azm email 1; Reham Helmy Abdel-Kareemorcid 2; Ahmed Salem Saber1; Hala Mahmoud Ahmed3
1faculty of medicine, Zagazig university
2Lecturer of Human Anatomy & Embryology
3Faculty of medicine, Zagazig university
Abstract
Background: Congenital hydrocephalus (CH) is a complicated syndrome that may be linked to a wide range of brain disabilities. It results from restricted cerebrospinal fluid flow either functionally or physically, causing advanced cerebral ventricular dilation and compression of brain tissue. The physical characteristics of CH are persistent open anterior fontanelle, dome shape head, and ventrolateral strabismus on both sides. There are also, headache, nausea, crossing normal centile lines, sunset eyes, distended scalp veins, delayed development, poor feeding, as well as parinaud’s syndrome and possible abducent nerve palsy. CH is linked to variable risk factors including prematurity, congenital infections, maternal pathologies, medications, alcohol use, trauma and tumors. It may be related to other congenital abnormalities like spina bifida, aqueductal stenosis, Arnold-Chiari and Dandy-Walker anomalies. This review summarizes CH as regards the pathophysiology, risk factors, genetics, clinical picture, and associated CNS defects, providing information that can help in prevention of some cases of CH. Conclusion: Protection of infants against CH could be achieved by avoiding risk factors, early diagnosis and proper management
Keywords
Hydrocephalus; CSF; premature infant; congenital infection; neural tube defect
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