CALCIUM PHOSPHATE AS AN ADJUVANT FOR INACTIVATED RIFT VALLEY FEVER VACCINE | ||||
Egyptian Journal of Agricultural Research | ||||
Article 26, Volume 84, Issue 2, July 2006, Page 643-653 PDF (2.51 MB) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/ejar.2006.230689 | ||||
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Authors | ||||
KHAIRAT A. ELLIAN; LILLY S. SALAMA; ALFONS M. IBRAHIM; TARADI ABD - EL FATTEH; AHMED M. DAOUD | ||||
Veterinary Serum and Vaccine Research Institute, Agricultural Research Center, Ministry of Agriculture, Dokki, Giza, Egypt | ||||
Abstract | ||||
Vaccination to protect animal against infectious diseases may be enhanced by using adjuvants that can selectively stimulate immunoregulatory responses. A novel adjuvant composed of caldum phosphate (CAP) was compared with the commonly used aluminium hydradde (alum) gel adjuvant for its ability to Induce immunity to Rift Valley Fever virus. Results indicated that CAP was more potent as an adjuvant than alum, induced high titres of antibody. Furthermore, it is economical, simple to manufacture and it is a natural constituent of the animal body. | ||||
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