Characterization of Bioactive Compounds with Antioxidant Activity and Antimicrobial Activity from Freshwater Cyanobacteria.
Shawer, E., Sabae, S., El-Gamal, A., Elsaied, H. (2022). Characterization of Bioactive Compounds with Antioxidant Activity and Antimicrobial Activity from Freshwater Cyanobacteria.. EKB Journal Management System, 65(9), 723-735. doi: 10.21608/ejchem.2022.127880.5681
Ehab El-sayed Shawer; Shawky Zaki Sabae; Ahmed Darwish El-Gamal; Hosam Easa Elsaied. "Characterization of Bioactive Compounds with Antioxidant Activity and Antimicrobial Activity from Freshwater Cyanobacteria.". EKB Journal Management System, 65, 9, 2022, 723-735. doi: 10.21608/ejchem.2022.127880.5681
Shawer, E., Sabae, S., El-Gamal, A., Elsaied, H. (2022). 'Characterization of Bioactive Compounds with Antioxidant Activity and Antimicrobial Activity from Freshwater Cyanobacteria.', EKB Journal Management System, 65(9), pp. 723-735. doi: 10.21608/ejchem.2022.127880.5681
Shawer, E., Sabae, S., El-Gamal, A., Elsaied, H. Characterization of Bioactive Compounds with Antioxidant Activity and Antimicrobial Activity from Freshwater Cyanobacteria.. EKB Journal Management System, 2022; 65(9): 723-735. doi: 10.21608/ejchem.2022.127880.5681

Characterization of Bioactive Compounds with Antioxidant Activity and Antimicrobial Activity from Freshwater Cyanobacteria.

Egyptian Journal of Chemistry
Article 66, Volume 65, Issue 9, September 2022, Page 723-735  XML PDF (625.25 K)
Document Type: Original Article
DOI: 10.21608/ejchem.2022.127880.5681
View on SCiNiTO View on SCiNiTO
Authors
Ehab El-sayed Shawer email orcid 1; Shawky Zaki Sabae1; Ahmed Darwish El-Gamal2; Hosam Easa Elsaied1
1National Institute of Oceanography and Fisheries (NIOF), Egypt.
2Botany and Microbiology Department, Faculty of Science, Al-Azhar University, Nasr City, Cairo, Egypt
Abstract
Cyanobacteria are one of the most promising candidates for production of alternative biomolecules that can be used for biotechnological applications. In the current study the methanolic extract from four cyanobacterial isolates were screened for their total phenolics, total flavonoids contents, antioxidant and antimicrobial activities. The highest total phenolic content) 14.33±0.76 mg GAE/g DW) was detected in Oscillatoria sancta SN2 (MZ504750) extract while the highest flavonoid content (3.13±0.04 mg QE/g DW) was recorded for Limnothrix planktonica SN4 (MZ504752). All extracts were discovered to have antioxidant activity against 2,2-diphenyl-1-picrylhydrazyl (DPPH) and the IC50 values ranged between 1.61 mg/ml to 5.68 mg/ml for Limnothrix planktonica SN3 (MZ504751) and Oscillatoria sancta (SN2 MZ504750) respectively. The extracts were examined for antimicrobial activity and showed varying degrees of activity against various gram negative, gram positive bacteria and yeast. GC/MS analysis showed that all extracts contain numerous active biomolecules including 3Allyl-6-methoxyphenol, cis-Vaccenic acid, cis-13-Eicosenoic acid, Tetradecanoic acid "Myristic acid", Phytol, Palmitoleic acid, Palmitic acid methyl ester, n-Hexadecanoic acid "Palmitic acid", Linolenic acid methyl ester, Linolenic acid, and other compounds which exerts antimicrobial and antioxidant activity.
Keywords
Cyanobacterial extracts; Phenolic compounds; flavonoids; Antimicrobial activity; Antioxidant activity; GC – MS
Statistics
Article View: 849
PDF Download: 1,080