Biocompatibility evaluation of of 3 different intracanal medicaments (A histological study) | ||
Egyptian Dental Journal | ||
Article 9, Volume 68, Issue 2 - Serial Number 5, April 2022, Pages 1849-1857 PDF (1.02 M) | ||
Document Type: Original Article | ||
DOI: 10.21608/edj.2022.90649.1753 | ||
Authors | ||
Abeer Elgendy1; D Labah2; Fawzy Darweesh* 2 | ||
1Associate Professor, Department of Endodontic, Faculty of Oral and Dental Medicine, Zagazig University | ||
2Associate Professor, Department of Oral Biology, Faculty of Oral and Dental Medicine, Zagazig University | ||
Abstract | ||
Abstract: Background: To analyze tissue responses of Wistar rats to calcium hydroxide (calcipast), calcium hydroxide iodoform (calcipaste fort) and 2% chlorhexidine gel intracanal medicaments at different implantation time intervals. Methods: 90 specimens were randomly implanted subcutaneously of rats dorsal surface with a polyethylene tubes containing the following substances:, calcium hydroxide (calcipast), 2% chlorhexidine gel and calcium hydroxide iodoform (calcipaste fort) intracanal medicaments (test groups). However subcuateneous implantations of 30 specimens of empty polyethylene tubes (control group) were performed; Rats were distributed according to time intervals of evaluation at 1, 2 and 4 weeks. The histological sections were stained with Harris hematoxylin and eosin then evaluations were made in a digital Microscope at X40, X100, and X400 magnifications for quantitative evaluations of inflammatory cells. Results: It was observed that between the tested materials, calcipast fort |(group 4) showed the least inflammatory rats tissue reaction , followed by chlorohexidine (group 3) then calcipast group (group 2) at all tested time intervals in comparison to control group (group1). Conclusion: Calcipast fort showed good biocompatibility when compared with chlorohexidine and calcipast intracanal medications. | ||
Keywords | ||
KEYWORDS: Biocompatibility; Calcium hydroxide; iodoform and Chlorhexidine | ||
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