A validated multiresidue method for the determination of 34 pesticide residues in different types of tea bags using QuEChERS method with LC-ESI-MS/MS
Ibrahim, H., El-Gindy, A., Hadad, G., Badr, J., Ali, E. (2022). A validated multiresidue method for the determination of 34 pesticide residues in different types of tea bags using QuEChERS method with LC-ESI-MS/MS. EKB Journal Management System, 6(1), 10-27. doi: 10.21608/rpbs.2021.112458.1120
Hanan Samir Ibrahim; Alaa El deen Mohamed El-Gindy; Ghada Hadad; Jihan Badr; El sayed ibrahim Ali. "A validated multiresidue method for the determination of 34 pesticide residues in different types of tea bags using QuEChERS method with LC-ESI-MS/MS". EKB Journal Management System, 6, 1, 2022, 10-27. doi: 10.21608/rpbs.2021.112458.1120
Ibrahim, H., El-Gindy, A., Hadad, G., Badr, J., Ali, E. (2022). 'A validated multiresidue method for the determination of 34 pesticide residues in different types of tea bags using QuEChERS method with LC-ESI-MS/MS', EKB Journal Management System, 6(1), pp. 10-27. doi: 10.21608/rpbs.2021.112458.1120
Ibrahim, H., El-Gindy, A., Hadad, G., Badr, J., Ali, E. A validated multiresidue method for the determination of 34 pesticide residues in different types of tea bags using QuEChERS method with LC-ESI-MS/MS. EKB Journal Management System, 2022; 6(1): 10-27. doi: 10.21608/rpbs.2021.112458.1120

A validated multiresidue method for the determination of 34 pesticide residues in different types of tea bags using QuEChERS method with LC-ESI-MS/MS

Records of Pharmaceutical and Biomedical Sciences
Article 2, Volume 6, Issue 1, April 2022, Page 10-27  XML PDF (1.05 MB)
Document Type: Original Article
DOI: 10.21608/rpbs.2021.112458.1120
View on SCiNiTO View on SCiNiTO
Authors
Hanan Samir Ibrahim email 1; Alaa El deen Mohamed El-Gindy2; Ghada Hadadorcid 3; Jihan Badr4; El sayed ibrahim Ali5
1Analytical chemistry faculty of pharmacy Suez Canal university
2Department of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Suez Canal University, Ismailia, Egypt
3Analytical Chemistry Department, Faculty of Pharmacy, Suez Canal University, Ismailia, 41522, Egypt.
4Pharmacognosy Department, Faculty of Pharmacy, Suez Canal University, Ismailia, 41522, Egypt.
5analtical chemistry faculty of pharmacy suez canal university
Abstract
QuEChERS method. Phase separation and pesticide partitioning were performed by the addition of the extraction kits based on the EN-QuEChERS methodology. The LC-MS/MS analysis was conducted using an Agilent HPLC 1260 along with API 6500 QTRAP mass spectrometer and electro spray ionization (ESI) interface. The chromatographic separation was achieved using an Agilent C18 reverse-phase column ZORBAX Eclipse plus 4.6 × 150 mm with 5.0 μm particle size. The ESI was operated in the positive mode. A gradient elution program was used at 500 μL/min flow rate using 10 mM ammonium formate in 1% methanol and methanol.
The obtained results showed that, more than 34 pesticides have been detected in most of examined samples collected from different companies in the Egyptian market. Limit of quantitation for the studied pesticides was10µg/kg. It was found that some pesticide residues exceed Maximum Residue Level (MRL).
The optimized QuEChERS was validated according to accuracy, precision ,detection limit (LOD), quantification limit (LOQ) and it was successfully applied for detection of 34 pesticide residues in tea bags samples collected from the Egyptian market.
Keywords
Pesticides; Tea bags; QuEChERS; LC MS MS
Statistics
Article View: 371
PDF Download: 257