Polymeric nano sponge drug delivery system: A review | ||||
| Records of Pharmaceutical and Biomedical Sciences | ||||
| Article 4, Volume 6, Issue 3, April 2022, Page 34-58 PDF (1.3 MB) | ||||
| Document Type: Mini-reviews | ||||
| DOI: 10.21608/rpbs.2022.88495.1131 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Shadeed Gad   1; Sameh Alhussini2; Ahmed R. Gardouh 3
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| 1Faculty of Pharmacy - Suez Canal University | ||||
| 2Department of Research & Development, Alandalous for Pharmaceutical Industries, Egypt. | ||||
| 3Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Suez Canal University. | ||||
| Abstract | ||||
| Nanotechnology is redefining healthcare methods, and it is projected to have a significant impact in the next years, resulting in improved healthcare facilities. It has paved the way for therapeutic medication delivery and diagnostics. Medical nanoparticles are materials in the nanoscale (from 1 to 100 nm) employed in the development, production, control, and use of medicinal drugs or devices employed in developing, producing, controlling, and using medicinal drugs or devices. Aside from gene therapy, nano-based medicine delivery systems benefit cancer, diabetes, infectious diseases, neurological diseases, blood diseases, and orthopaedic-related maladies. Furthermore, the development of multifunctional nanotherapeutics is potentially needed to contribute to the present therapeutic area positively. Nanomedicines are preferable to conventional therapeutic approaches in cancer as they can transmit the drug efficiently to the damaged tissues, decreasing drug toxicity. Nanotechnology-based medicines and diagnostics are more effective while posing little or no side effects. Micelles of polymeric paclitaxel and polymeric asparaginase conjugates have been advocated for treating several tumours in this vein. Nanotechnology advancements have prepared nanorobotics to be applied in various healthcare applications. As a result, this review thoroughly highlights the potential of polymeric nanoparticles, Nano-emulsions, solid lipid nanoparticles, nanostructured lipid carriers, self-micellizing anticancer lipids, dendrimer, nanocapsule, and nanosponges approaches in cancer, as well as the potentialities of various nanocarriers and nanomedicines for a variety of applications in diagnostics and drug delivery. This article reviews the most recent literature on nanotechnology, particularly cyclodextrin-based polymers, in medicinal applications. | ||||
| Keywords | ||||
| Nanosponges; β-Cyclodextrine; Drug Delivery Systems, Solubility; Nanomedicine | ||||
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