Antialopecia Activity and IR-Spectrometry Characterization of Bioactive Compounds From Sansevieria trifasciata P.
Kasmawati, H., Mustarichie, R., Halimah, E., Ruslin, R., A Sida, N. (2022). Antialopecia Activity and IR-Spectrometry Characterization of Bioactive Compounds From Sansevieria trifasciata P.. EKB Journal Management System, 65(132), 19-24. doi: 10.21608/ejchem.2022.104463.4825
Henny Kasmawati; Resmi Mustarichie; Eli Halimah; Ruslin Ruslin; Nurramadhani A Sida. "Antialopecia Activity and IR-Spectrometry Characterization of Bioactive Compounds From Sansevieria trifasciata P.". EKB Journal Management System, 65, 132, 2022, 19-24. doi: 10.21608/ejchem.2022.104463.4825
Kasmawati, H., Mustarichie, R., Halimah, E., Ruslin, R., A Sida, N. (2022). 'Antialopecia Activity and IR-Spectrometry Characterization of Bioactive Compounds From Sansevieria trifasciata P.', EKB Journal Management System, 65(132), pp. 19-24. doi: 10.21608/ejchem.2022.104463.4825
Kasmawati, H., Mustarichie, R., Halimah, E., Ruslin, R., A Sida, N. Antialopecia Activity and IR-Spectrometry Characterization of Bioactive Compounds From Sansevieria trifasciata P.. EKB Journal Management System, 2022; 65(132): 19-24. doi: 10.21608/ejchem.2022.104463.4825

Antialopecia Activity and IR-Spectrometry Characterization of Bioactive Compounds From Sansevieria trifasciata P.

Egyptian Journal of Chemistry
Volume 65, Issue 132, December 2022, Page 19-24  XML PDF (709.31 K)
Document Type: Original Article
DOI: 10.21608/ejchem.2022.104463.4825
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Authors
Henny Kasmawati email orcid 1; Resmi Mustarichieorcid 2; Eli Halimah3; Ruslin Ruslin4; Nurramadhani A Sida5
1Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran; Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Halu Oleo
2Department of Analytical Pharmacy and Medicinal Chemistry, Faculty of Pharmacy, Universitas Padjadjaran
3Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran
4Department of Analytical Pharmacy and Medicinal Chemistry, Faculty of Pharmacy, Universitas Halu Oleo
5Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Halu Oleo
Abstract
Androgenetic Alopecia (AGA) causes more than 90% of alopecia cases. Drugs for the treatment of AGA have toxic and side effects, so it is necessary to find new drugs from the natural product, such as Sansevieria trifasciata. This study aims to determine the hair growth activity of subfraction from Sansevieria trifasciata and characterize the isolate using infrared spectroscopy. The fraction of Sansevieria trifasciata was separated using column chromatography. The hair growth activity using the modified Tanaka method. Skin biopsies of each rabbit stained with hematoxylin and eosin. The characterization of the isolate using infrared spectroscopy (FT-IR). The separation of fractions obtained six subfractions. The hair growth activity from subfraction-C was higher with the hair growth length of 2.80 cm ± 0.00 (p
Keywords
Alopecia; Infrared spectroscopy; Sansevieria trifasciata; Anagen; Telogen
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