Utility of Carbothiohydrazides in Synthesis of some New Heterocyclic Compounds with Five- and Six-Membered Rings | ||||
Sohag Journal of Sciences | ||||
Article 1, Volume 7, Issue 1, January 2022, Page 1-8 PDF (691.85 K) | ||||
Document Type: Regular Articles | ||||
DOI: 10.21608/sjsci.2022.233166 | ||||
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Authors | ||||
Amr H. Moustafa 1; Doaa H. Ahmed1; Mamdouh F. A. Mohamed2; M. T. El-Wassimy1 | ||||
1Department of Chemistry, Faculty of Science, Sohag University, Sohag 82524, Egypt | ||||
2Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Sohag University, Sohag, Egypt | ||||
Abstract | ||||
Abstract: In this work we studied the reaction of carbohydrazides with some reagents having electrophilic centers such as arylmethylenemalononitrile, aromatic aldehydes, bis(methylthio)methylenemalononitrile, dimethyl acetylene-dicarboxylate and cyanoguanidine. The resulting products are five-membered heterocyclic rings such as thiadiazoles, thiazoles, triazoles; and six-membered heterocyclic rings such as triazines. | ||||
Keywords | ||||
Carbothiohydrazide; Thiosemicarbazide; Thiocarbohydrazide; Triazole; Cyanoguanidine | ||||
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