Synthesis, Characterization, and biological activity of some Heterocyclic compounds that derived from Ibuprofen | ||||
| Egyptian Journal of Chemistry | ||||
| Volume 65, Issue 11, November 2022, Page 795-802 PDF (1.03 MB) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ejchem.2022.135334.5950 | ||||
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| Authors | ||||
Hamid Mohammed Saleh Al-Jubori1; Tahseen Saddam Fandi Al-Mathkuri   2
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| 1Department of Science, College of Basic Education/Shirqat, Tikrit University, Tikrit, Iraq | ||||
| 2Department of Chemistry, College of Science, University of Misan, Maysan, Iraq | ||||
| Abstract | ||||
| A simple, easy method for preparation of new thiazoldine derivatives was done and new compound were elucidated on bases of spectroscopic analyses. Ibuprofen reacted with hydrazine hydrate to afford hydrazide derivative which reacted with aldehydes to afford Schiff bases that cyclized with Thioglycolic acid to afford thiazolidine derivatives. Antimicrobial activity of new compounds was carried out using diffusion plate method. | ||||
| Keywords | ||||
| Thizaolidine derivatives; Antimicrobial Activity; spectroscopic analyses | ||||
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