Comparative Study Between The Efficacy of Ozone Gel and Hyaluronic Acid on Bone Healing After Enucleation of Mandibular Odontogenic Cysts | ||||
| Al-Azhar Assiut Dental Journal | ||||
| Article 10, Volume 5, Issue 1 - Serial Number 33795, April 2022, Page 85-95 PDF (3.4 MB) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/aadj.2022.234799 | ||||
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| Authors | ||||
abdelbadia abdallah abdelmabood   1; Mohamed H. Eid2
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| 1Department of Oral and maxillofacial surgery, Faculty of Dental Medicine &Oral surgery ,Zagazig University, Sharqiua, Egypt. | ||||
| 2Department of Oral and maxillofacial surgery, Faculty of Dentistry, Suez Canal University, Ismalia, Egypt | ||||
| Abstract | ||||
| Aim: The aim of this study was to evaluate the clinical and radiographic effect of both Ozone gel and Hyaluronic acid after enucleation of mandibular odontogenic cysts. Subjects and methods: 24 patients complained of an odontogenic cystic lesion in mandible classified into three groups, Group I (Ozone group): Included 8 patients with odontogenic cysts treated by Enucleation followed by Ozone gel application in the surgical cavity. Group II (HA group): Included 8 patients with odontogenic cysts treated by Enucleation followed by Hyaluronic acid application in the surgical cavity. Group III ( Control group): Included 8 patients with odontogenic cysts treated by Enucleation only. Postoperative one-month panoramic view, 3, 6 cone-beam C.T as the radiographic follow-up. Facial edema, pain, and trismus were the clinical parameters at 1,3 and 7 days. Results: The study showed a significant increase in the bone density of both group I (ozone), II (Hyaluronic acid) than the control group comparing the percentage of bone density to the contralateral bone, it was for group I (Ozone group) 45.8%, 69% at follow up of 3,6, months. In group II ( HA ) it was for 51.9%, 72% at follow up of 3, 6, months. It was for group III (control group) 32.6%, 56.1% at follow up of 3, 6, 9 months as there was high statistical significance between-group I, II in comparing with the group I with P-value = 0.04,0.05..Conclusion: Both ozone gel and Hyaluronic acid can be considered to enhance bone regeneration after cystic enucleation due to their specific antimicrobial, anti-inflammatory properties, and increasing angiogenesis in the post-surgical cavities. | ||||
| Keywords | ||||
| Hyaluronic Acid; Ozone gel; odontogenic mandibular cysts; enucleation; antimicrobial | ||||
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