TORCH INFECTIONS, PATHOGENICITY & MORTALITY ASSESSMENTS
MORSY, T., HUSSEIN, H., MORSY, A. (2022). TORCH INFECTIONS, PATHOGENICITY & MORTALITY ASSESSMENTS. EKB Journal Management System, 52(1), 53-70. doi: 10.21608/jesp.2022.235777
TOSSON A. MORSY; HUSSEIN ELSAYED HUSSEIN; AYMAN T. A. MORSY. "TORCH INFECTIONS, PATHOGENICITY & MORTALITY ASSESSMENTS". EKB Journal Management System, 52, 1, 2022, 53-70. doi: 10.21608/jesp.2022.235777
MORSY, T., HUSSEIN, H., MORSY, A. (2022). 'TORCH INFECTIONS, PATHOGENICITY & MORTALITY ASSESSMENTS', EKB Journal Management System, 52(1), pp. 53-70. doi: 10.21608/jesp.2022.235777
MORSY, T., HUSSEIN, H., MORSY, A. TORCH INFECTIONS, PATHOGENICITY & MORTALITY ASSESSMENTS. EKB Journal Management System, 2022; 52(1): 53-70. doi: 10.21608/jesp.2022.235777

TORCH INFECTIONS, PATHOGENICITY & MORTALITY ASSESSMENTS

Journal of the Egyptian Society of Parasitology
Article 8, Volume 52, Issue 1, May 2022, Page 53-70  XML PDF (787.15 K)
Document Type: Original Article
DOI: 10.21608/jesp.2022.235777
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Authors
TOSSON A. MORSY1; HUSSEIN ELSAYED HUSSEIN2; AYMAN T. A. MORSY3
1Department of Parasitology, Faculty of Medicine, Ain-Shams University, Cairo 11566
2Consultant of Pathology, Military Medical Academy, Cairo, 11291
3Consultant of Endemic Diseases, Misr University for Science and Technology, Egypt
Abstract
A TORCH infection, also known as TORCH syndrome, is an infection of the developing fetus or
newborn that can occur in utero, during delivery, or after birth. TORCH syndrome is a cluster of
symptoms caused by congenital infection with toxoplasmosis, rubella, cytomegalovirus, Herpes
simplex, and other organisms including syphilis, parvovirus, and Varicella zoster as well as Zika
virus and others. TORCH syndrome is caused by in-utero infection with one of the TORCH
agents, disrupting fetal development. Early diagnosis by specific IgM and persistence of IgG
beyond 6-9 months is diagnostic. TORCH syndrome may develop before birth, causing stillbirth,
in the neonatal period, or later in life, refers very broadly pathogens that cause perinatal infection
and contribute to neonatal morbidity and mortality. They can cause non-specific signs
and symptoms in the fetus or infant, such as microcephaly, lethargy, cataracts, hearing loss, and
congenital heart diseases. Other signs include hepatosplenomegaly, petechiae or purpura,
jaundice, vision loss, intellectual disability, deafness, and seizures. Treatment of pregnancy
women is supportive and depends on symptoms present and thereby preventing the infection
from affecting the fetus.
Keywords
Toxoplasmosis; Other agents; Rubella Cytomegalovirus; Herpes simplex; Overview
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