Synthesis, studying analytical properties and biological activity of new transition metal complexes with sulfadiazine derivative as reagent | ||||
| Egyptian Journal of Chemistry | ||||
| Volume 66, Issue 1, January 2023, Page 55-61 PDF (801.96 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ejchem.2022.104212.4814 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Ghusoon Jawad Abbas1; Zaied Mosaa2; Ali Jabbar Radhi  3; Hayder Kadhim Abbas4; Walaa Mohammed Najem4
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| 1Branch of Biochemistry, Faculty of Medicine,Jabir ibn Hayyan Medical University | ||||
| 2College of science for women, University of Babylon, Hilla, Iraq. | ||||
| 3Faculty of Pharmacy, Al-Kafeel University, Najaf, Iraq. | ||||
| 4College of Pharmacy, University of Al-Kafeel, Najaf, Iraq. | ||||
| Abstract | ||||
| A new of nickel(II) and copper(II) complexes of 4-((4-acetylphenyl)diazenyl)-3-amino-N-(pyrimidin-2-yl) benzenesulfonamide (SDA) derived from sulfadiazine have been prepared and identified by FTIR, NMR, mass spectroscopy, UV-Visible spectroscopy, and elemental analysis. Also tested to evaluated their activities as antibacterial agents. The spectroscopic and analytical data suggest all prepared nickel(II) and copper(II) complexes a square planar geometry. The agar well diffusion method was used to test the target ligand and their Ni(II) and Cu(II) complexes for antibacterial activity against Gram (+) and Gram (-) bacteria. | ||||
| Keywords | ||||
| Antibacterial Activity; Sulfadiazine; Azo compound; Complexes | ||||
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