Application of Thiourea Polyurethane@Copper Sulfide Composite for Antibacterial Potential | ||||
Egyptian Journal of Chemistry | ||||
Volume 66, Issue 1, January 2023, Page 31-36 PDF (751.61 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/ejchem.2022.125302.5573 | ||||
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Authors | ||||
Mohamed M. El-Zahed 1; Hala A. Kiwaan2; Asmaa A.M. Farhat2; Elhossein A. Moawed2; Mervat A. El-Sonbati 3 | ||||
1Department of Botany and Microbiology, Faculty of Science, Damietta University, New Damietta, Egypt | ||||
2Chemistry Department, Faculty of Science, Damietta University, Egypt | ||||
3Environmental Sciences Department, Faculty of Science, Damietta University, Egypt | ||||
Abstract | ||||
This work synthesized a new composite by coupling copper sulfide nanoparticles and isothiouronium polyurethane foam to enhance antimicrobial activity. Fourier transform infrared (FTIR), ultraviolet-visible spectra (UV/Vis), point zero charge (pHpzc), acidic and basic sites, iodine number, methylene blue value, energy disperse (EDX), X-ray diffraction (XRD), and scan electron microscopy (SEM) were used to characterize isothiouronium polyurethane@copper sulfide foam composite (ITPU@CuS). The antibacterial activity of ITPU@CuS was tested against Gram-positive (Bacillus cereus) and Gram-negative (Pseudomonas aeruginosa). The biocidal action of ITPU@CuS against the microbial strains was significantly higher at the concentration of 150 μg/ml than at lower concentrations. Also, transmission electron microscopy (TEM) of the ITPU@CuS-treated bacteria was studied. TEM micrographs of the treated bacteria confirmed the bactericidal action of ITPU@CuS by showing malformation action, wrinkling, and bacterial cell wall damage. The obtained composite could be considered to be a promising material aimed at industry, especially in the field of food packaging, where it is effective against pathogenic microbes. | ||||
Keywords | ||||
polyurethane foam composite; copper sulfide; antibacterial activity; Bacillus cereus; Pseudomonas aeruginosa | ||||
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