Antioxidant Potential of Eight selected Kenyan Medicinal plants | ||||
| Egyptian Journal of Chemistry | ||||
| Volume 66, Issue 1, January 2023, Page 545-553 PDF (673.22 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ejchem.2022.127658.5666 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Mohamed Abd-elfattah 1, 2; Naomi Maina1, 3; Patrick Gachoki Kareru3; Hany A. El-Shemy1, 4
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| 1Department of Molecular Biology and Biotechnology, Pan African University Institute of Science, Technology and Innovation, JKUAT campus, Juja, Nairobi, 62000, 00200, Kenya. | ||||
| 2Special Food and Nutriation Res.Department, Food Tech. Res. Institute, Agricultural Research Center, Giza, 12613 Egypt. | ||||
| 3Chemistry Department, Jomo Kenyatta University of Agriculture and Technology, Juja, Nairobi, 62000, 00200, Kenya. | ||||
| 4Department of Biochemistry, Faculty of Agriculture, Cairo University, Giza,12613 Egypt | ||||
| Abstract | ||||
| Adding of antioxidants to our daily food may reduce the risk of diseases caused by free radicals as a result of oxidative stress in the human body. In this study, eight selected Kenyan medicinal plants (Terminalia brownii, Aloe secundiflora, Prunus africana, Carissa edulis, Tithonia diversifolia, Warburgia ugandensis, Croton megalocarpus and Launaea cornuta) were studied for their potential antioxidant activity. The levels of polyphenols and flavonoids were determined using standard methods. Plant parts were extracted using water and different organic solvents. Prunus africana acetone extract had the highest levels of phenolic compounds while Tithonia diversifolia water extract had the lowest amount. The antioxidant activity was highest in Terminalia brownii acetone extract and lowest in Croton megalocarpus, Diethyl ether leaves extract, respectively. This trend was followed by antioxidant potency composite index of the medicinal plant extracts. Terminalia brownii extracts had the highest antioxidant activity and potential, followed by Prunus africana extracts due to the higher total phenolic content found in the latter medicinal plants. Total phenolic content was positively correlated with FRAP, ABTS and DPPH values. Based on the antioxidant potency composite index calculated and the overall antioxidant index, it can be concluded that the extracts from T. brownii bark and P. africana bark can be recommended as a potential natural source of antioxidants appropriate for utilization in nutritional and pharmaceutical fields. Further evaluation of the bioactive compounds and antioxidant activities in living models need to be investigated. | ||||
| Keywords | ||||
| Antioxidant activity; DPPH; ABTS; FRAP; free radicals; polyphenols; flavonoids | ||||
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