Creatine Kinase as a diagnostic biochemical Marker in Placenta Accreta, Mansoura experience | ||||
| The Egyptian Journal of Fertility of Sterility | ||||
| Article 3, Volume 26, Issue 2, May 2022, Page 13-20 PDF (1.8 MB) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/egyfs.2022.237722 | ||||
 View on SCiNiTO | ||||
| Author | ||||
| mohamed ibrahem eid | ||||
| mansoura university obstetrics and gynecology dep | ||||
| Abstract | ||||
| Abstract Background: placenta accreta is a life-threatening pregnancy complication which usually accompanied with placenta previa. It is important to make the diagnosis before delivery therefore a preoperative planning will decrease complications. The aim of this study was to evaluate the possibility of using creatine kinase as a diagnostic and prognostic marker in placenta accreta. Methods: two groups were recruited; forty-five patients diagnosed by ultrasound with placenta accreta as patient group (group A) and another forty-five as controls (group < br />B). Maternal Creatine kinase level was measured using CKNAC FS* IFCC Technical bulletin and compared between patients group and controls group. Results: Our results indicated the presence of significant difference between the patient group and the control group < br />regarding age (P-value= 0.01), gravidity (P-value= 0.01) and parity (P-value= 0.006). While non-significant difference regarding medical history (P-value= 0.59), surgical history (P-value= 0.51), and D & C (P-value= 0.82). Our results indicated no significant difference between both groups regarding serum creatine kinase level (P-value= 0.29). We have identified surgical complications and intraoperative findings which occurred significantly higher in the patient group in compare with the control group (P value <0.001). Our finding also revealed the presence of significant difference between the patient and control group regarding secondary outcomes including the required blood units transfusion (P-value <0.001). Conclusion: We conclude that maternal serum creatine kinase is not a reliable tool in predicting or diagnosing placenta accreta. | ||||
| Keywords | ||||
| Keywords: Creatine kinase; placenta accreta; previa; ultrasonography; surgical outcome | ||||
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