Determination of rate constants and half-life times of complexes derived from coupling reaction 2,4-dinitroaniline and two electron-donating compounds | ||||
| Egyptian Journal of Chemistry | ||||
| Volume 66, Issue 2, February 2023, Page 339-347 PDF (703.02 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ejchem.2022.133953.5908 | ||||
 View on SCiNiTO | ||||
| Author | ||||
Dr. Mohammad Mahmoud Hussein Al-Niemi 
| ||||
| Dept. of chemistry/ Collage of education for pure sciences / Mosul university /Mosul / Iraq | ||||
| Abstract | ||||
| The research included a study of the kinetic reactions for the colored produced complexes derived from two different electron-donating drugs (Salicylic acid and Paracetamol) with a diazotized reagent (2,4-dinitroaniline) that accepts these electrons at different pH functions and a constant temperature (298°K). The optimal conditions were determined for each complex formed as well as the optimal ratios (stoichiometry) of its components, which were (1:10) for (drug: reagent) respectively. Then, the kinetics of the formation for the above complexes was followed spectroscopically, and it was found that these interactions was proved that drug complex formation followed a Pseudo-first-order kinetic with respect to Salicylic acid or Paracetamol drug. We were able to calculate the rate constant(k1) for the formation of the two produced drug compounds. The highest value(k1) for the drug complex (SADDNA: Salicylic Acid Drug + Diazotized 2,4-Dinitroaniline) is (0.0457 at pH7), and for the drug complex (PDDNA: Paracetamol Drug + Diazotized 2,4-Dinitroaniline) is (0.0314 at pH9). We also calculated the half-life-time(t1/2) for each of them, and it was (15.17min.) and (22.08min.), respectively, which is completely opposite to the values of their rate constants under the same conditions. | ||||
| Keywords | ||||
| 2; 4-dinitroaniline; kinetic rate-constant; pseudo-first-order kinetic; diazotized reagent; Stoichiometry; half-life-time | ||||
|
Statistics Article View: 264 PDF Download: 111 |
||||
