POSSIBILITY OF ALLEVIATING F000BORNE AFLATOXICOSIS EFFECTS ON PERFORMANCE AND BIOCHEMISTRY OF MALE ALBINO WHITE RATS | ||||
| Journal of Animal and Poultry Production | ||||
| Article 2, Volume 30, Issue 2, February 2005, Page 833-849 PDF (234.69 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/jappmu.2005.237960 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
| A. M. Abdeihamid,1; Kh. M. EI-MeIeigy2; Amal M. Ahmed2 | ||||
| 1Animal Production Department, Faculty of Agriculture, Mansoura University, Egypt | ||||
| 2Central Lab. of Foods and Feeds, Ministry of Agriculture, Cairo, Egypt | ||||
| Abstract | ||||
| One hundred and twenty six albino male rats (average initial body weight of 105 g) were divided into 14 dietary groups (3 replicates X 3 animals/group). They fed for 21 weeks on a control (C) diet, C + 0.5% or 1% tafia1 C + 1 or 3% ammonia, C ÷ 3 or 6% H202, C + 1000 ppb afiatoxin (A), A + tafia or ammonia or H202 (at the same previous levels). The animals were housed in wire cages and fed ad libitum and water was available for 24 hours daily. The obtained results cleared that feeding rats on the aflatoxin( AF)-diet alone depressed the live body weight, daily body weight gain, feed intake, feed efficiency and increased mortality rate. The reduction in live BW was increased with the progress of feeding period, being 28.3% at 13 weeks old and 41.3% at 21 weeks old. Addition of different additives (tafia, ammonia and hydrogen peroxide) to the AF-diet decreased the deleterious effects of aflatoxin on rats performance compared with those fed the AF-diet alone. However, the effective additive lo protect against the negative effect of afiatoxin was tafia. Aflatoxin excreted in faeces (as % of intake) was higher in rats fed the AF-diet with different additives than in those fed the AF-diet alone. Rats fed the AF-diet alone had higher level of serum urea-N, uric acid, creatinine, ASTI ALT and alkaline phosphatase and lower levels of serum cholesterol, triglycerides, total protein and albumin than those fed the uncontaminated diet (control). Addition of different additives to the AF-diet decreased the deleterious effects of afiatoxin on blood parameters. Tafia was the best additive to protect against the negative effect of aflatoxin on blood. The relative weights of the internal organs (liver, kidneys, spleen, testes, heart and lungs) increased by feeding the contaminated diets. The different dietary additives did not improve the toxic effects of afiatoxin. Therefore it becomes clear to what extent is the seriousness of foodborne aflatoxicosis by animals (and consequently consumers). Even adsorbents (although they slightly reduce absorption) still neither obstacle nor sufficient mean for removing afiatoxins and its toxic effects. Where it is to impose upon the concern of prophyaxis against fungal invasion of feedstuffs and their ingredients to prevent consequently mycotoxin production on feeds. | ||||
| Keywords | ||||
| Rats; Ai9atoxin; Performance; Feed efficincy; Biochemical parameters | ||||
|
Statistics Article View: 39 PDF Download: 130 |
||||
