Protective Effect of Moringa and Sage on Fertility Impairment Induced by Synthetic Pyrethroids in Male Rats
El-Defrawy, S., Sobhy, H., El-Kholy, T., El-Hashash, S., Sultan, H. (2020). Protective Effect of Moringa and Sage on Fertility Impairment Induced by Synthetic Pyrethroids in Male Rats. EKB Journal Management System, 6(2), 13-27. doi: 10.21608/ejceh.2020.238155
Samar H. Sh. El-Defrawy; Hanan M. Sobhy; Thanaa A. El-Kholy; Samah A. El-Hashash; Hanan A. Sultan. "Protective Effect of Moringa and Sage on Fertility Impairment Induced by Synthetic Pyrethroids in Male Rats". EKB Journal Management System, 6, 2, 2020, 13-27. doi: 10.21608/ejceh.2020.238155
El-Defrawy, S., Sobhy, H., El-Kholy, T., El-Hashash, S., Sultan, H. (2020). 'Protective Effect of Moringa and Sage on Fertility Impairment Induced by Synthetic Pyrethroids in Male Rats', EKB Journal Management System, 6(2), pp. 13-27. doi: 10.21608/ejceh.2020.238155
El-Defrawy, S., Sobhy, H., El-Kholy, T., El-Hashash, S., Sultan, H. Protective Effect of Moringa and Sage on Fertility Impairment Induced by Synthetic Pyrethroids in Male Rats. EKB Journal Management System, 2020; 6(2): 13-27. doi: 10.21608/ejceh.2020.238155

Protective Effect of Moringa and Sage on Fertility Impairment Induced by Synthetic Pyrethroids in Male Rats

Egyptian Journal of Chemistry and Environmental Health
Volume 6, Issue 2, November 2020, Page 13-27  XML PDF (522.64 K)
Document Type: Scientific and Research
DOI: 10.21608/ejceh.2020.238155
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Authors
Samar H. Sh. El-Defrawy1; Hanan M. Sobhy email 2; Thanaa A. El-Kholy3; Samah A. El-Hashash3; Hanan A. Sultan4
1Nutrition and food science.Dept., Faculty of Home Economics Al-Azhar university
2BiochemToxicol& Food Deff.Dep - Animal Health Research Institute
3Nutrition and food science. Dep – Faculty of Home Economics Al – Azhar university
4Nutrition Dep- Research Institute of Ophthalmology( RIO)
Abstract
The main objective of this study was to investigate the efficiency ofMoringa and sage leaves as protective agents on deltamethrin–induced morphological and functional changes in gonads of male albino rats. Dry Moringa and sage leaves were chemically analyzed in order to identify their nutritive values. For the biological study fifty four adult normal male albino rats (Sprague Dawley strain) of an average body weight 150-180 g were divided into 9 groups of 6 rats each including control (-ve) group, control (+ ve) group 1 (administered deltamethrin orally at 10mg/kg b.wt.), control (+ ve) group 2 (administered deltamethrin orally at 5mg/kg b.wt.The 4th and 5th groups were fed on standard ration containing Moringa and sage leaf powders at 5 and 2.5%, respectively, while the 6th and 7 th groups were fed on standard ration containing Moringa leaves powder (5%) and received deltamethrin (10 and 5mg/kg b.wt., respectively), and the 8 th and 9th groups were fed on standard ration containing sage leaves powder (2.5%) and received deltamethrin (10 and 5mg/kg b.wt., respectively). Feeding trial continued for 30 successive days. Results indicated the high nutritional values of Moringa and sage leaves. Although deltamethrin administration at its two doses did not affect the relative weights of sexual organs including testis, seminal vesicle glandsepididymis and prostateit caused significant reductions in both sperm cell count and motility while sperm abnormalities including bent head and detached tail were significantly increased.It can be concluded that supplementation of daily meals with dried Moringa and sage leaves are recommended to prevent from infertility resulted from exposure to deltamethrin. 
Keywords
Moringa; Sage; Fertility
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