Synthesis of Some Novel Pyridine, Sulfonamide, Coumarin and Thiophene Derivatives | ||||
| Egyptian Journal of Chemistry | ||||
| Volume 66, Issue 2, February 2023, Page 349-355 PDF (611.48 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ejchem.2022.135732.5979 | ||||
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| Authors | ||||
Ammar H. Al-Sabawi   1; Shahla A. Younis 1; Rana A. Saeed2
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| 1Department of Chemistry, College of Science, University of Mosul, Mosul, IRAQ | ||||
| 2Department of Pharmaceutical, Mosul Technical Institute, Northern Technical University, Mosul, IRAQ. | ||||
| Abstract | ||||
| A series of novel pyridine, sulfonamide, coumarin, thiophene, α,β-unsaturated carbonyl compounds, and pyrazole derivatives were synthesized from hydrazide-hydrazone derivatives with different reagents (substituted benzaldehydes, hydrazine hydrate, malononitrile, 2-hydroxy-1-naphthaldehyde, tetralone, cyclopentanone, and ethyl cyanoacetate). Hydrazide-hydrazone derivatives were prepared by reactions 2-cyanoacetohydrazide with 2-acetylpyridine or 4-acetyl-N-(p-tolyl)benzenesulfonamide. On the basis of their spectral information, the structures of the newly synthesized chemical derivatives were determined. | ||||
| Keywords | ||||
| 2-cyanoaceto hydrazide; 4-acetyl-N-(p-tolyl)benzenesulfonamide; pyridine; sulfonamide; coumarin; thiophene; and pyrazoles derivatives | ||||
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