Histopathological alterations in liver, kidney, and testis of obese male albino rats following thunder god vine roots extract treatment
Elfatairy, N., Abbas, O., Khashaba, M., Khalaf, A. (2023). Histopathological alterations in liver, kidney, and testis of obese male albino rats following thunder god vine roots extract treatment. EKB Journal Management System, 4(1), 41-50. doi: 10.21608/ajbas.2022.137511.1099
Nrmeen Elsayed Elfatairy; Osama Ahmed Abbas; Marwa Hosny Khashaba; Ahmed Khalaf. "Histopathological alterations in liver, kidney, and testis of obese male albino rats following thunder god vine roots extract treatment". EKB Journal Management System, 4, 1, 2023, 41-50. doi: 10.21608/ajbas.2022.137511.1099
Elfatairy, N., Abbas, O., Khashaba, M., Khalaf, A. (2023). 'Histopathological alterations in liver, kidney, and testis of obese male albino rats following thunder god vine roots extract treatment', EKB Journal Management System, 4(1), pp. 41-50. doi: 10.21608/ajbas.2022.137511.1099
Elfatairy, N., Abbas, O., Khashaba, M., Khalaf, A. Histopathological alterations in liver, kidney, and testis of obese male albino rats following thunder god vine roots extract treatment. EKB Journal Management System, 2023; 4(1): 41-50. doi: 10.21608/ajbas.2022.137511.1099

Histopathological alterations in liver, kidney, and testis of obese male albino rats following thunder god vine roots extract treatment

Alfarama Journal of Basic & Applied Sciences
Article 4, Volume 4, Issue 1, January 2023, Page 41-50  XML PDF (501.86 K)
Document Type: Review Article
DOI: 10.21608/ajbas.2022.137511.1099
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Authors
Nrmeen Elsayed Elfatairy email 1; Osama Ahmed Abbas2; Marwa Hosny Khashaba3; Ahmed Khalaf4
1Zoology Department, Faculty of science, Port Said University
2Zoology Department, Faculty of Science, Port Said University, Port Said, Egypt.
3Pathology Department, Faculty of Medicine, Port Said University
4Department of Zoology, Faculty of Science, Port Said University
Abstract
Obesity is a multi-factor chronic condition caused by a amalgamation of genetics, environment, and an energy intake/expension imbalance. Modern civilization is seeing a significant growth in obesity, as well as an increased risk of metabolic syndromes in the general population due to lifestyle change. Even though obesity is a medical problem, maintaining individual's quality of life will require weight control. Weight loss goals is to reduce health risks, promote weight loss, and prevent weight gain . Weight management herbs include thunder god vine (roots).. Herbs like thunder god vine (roots) are used for weight management. Various laboratory studies proved that using thunder god vine extract might causes damage to multiple organs and tissues, and is fatal in some cases. The goal of this study is to measure toxicity of two doses of thunder god vine root extract, low 5mg/kg and high 7.5mg/kg, on the liver, kidney, and testis tissues of fat diet-induced obese male rats.. Histological examination of the obtained sections of all animal groups revealed that treatment with two different doses of the extract in obese rats showed no changes in the seminiferous tubules and different stages of spermatogenesis in testis and. Liver injury and nephrotoxic effects were reported after treatment with the plant extract at with two doses.
Keywords
Tripterygium wilfordii; Toxicity; Organs; Obesity; Histopathology
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