Chemical Analysis and Antibacterial Activity of Glycyrrhiza glabra roots
Al Mousawi, H., Saleh, R., Omran, A., Al Sa'ady, A., Ghasemian, A. (2022). Chemical Analysis and Antibacterial Activity of Glycyrrhiza glabra roots. EKB Journal Management System, 65(10), 667-672. doi: 10.21608/ejchem.2022.117422.5294
Heyam G. Al Mousawi; Rasha Hadi Saleh; Aseel Mohammed Omran; Amal Talib Al Sa'ady; Abdolmajid Ghasemian. "Chemical Analysis and Antibacterial Activity of Glycyrrhiza glabra roots". EKB Journal Management System, 65, 10, 2022, 667-672. doi: 10.21608/ejchem.2022.117422.5294
Al Mousawi, H., Saleh, R., Omran, A., Al Sa'ady, A., Ghasemian, A. (2022). 'Chemical Analysis and Antibacterial Activity of Glycyrrhiza glabra roots', EKB Journal Management System, 65(10), pp. 667-672. doi: 10.21608/ejchem.2022.117422.5294
Al Mousawi, H., Saleh, R., Omran, A., Al Sa'ady, A., Ghasemian, A. Chemical Analysis and Antibacterial Activity of Glycyrrhiza glabra roots. EKB Journal Management System, 2022; 65(10): 667-672. doi: 10.21608/ejchem.2022.117422.5294

Chemical Analysis and Antibacterial Activity of Glycyrrhiza glabra roots

Egyptian Journal of Chemistry
Article 64, Volume 65, Issue 10, October 2022, Page 667-672  XML PDF (299.38 K)
Document Type: Original Article
DOI: 10.21608/ejchem.2022.117422.5294
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Authors
Heyam G. Al Mousawi1; Rasha Hadi Saleh1; Aseel Mohammed Omran1; Amal Talib Al Sa'ady email orcid 1; Abdolmajid Ghasemianorcid 2
1College of Pharmacy/University of Babylon ,Iraq
2Noncommunicable Diseases Research Center, School of Medicine, Fasa University of Medical Sciences, Fasa, Iran
Abstract
Glycyrrhiza glabra roots contain high nutritive value and substantial medicinal properties such as antibacterial, antioxidant, antimalarial, antispasmodic, anti-inflammatory and anti-hyper glycemic activities. Plant samples were collected from Babylon governorate, Iraq. Confirmed classification of G. glabra and preparation of root extract were implemented in the laboratories of college pharmacy/university of Babylon. Various extracts and chemical compounds were obtained and the antimicrobial effects of G. glabra was assessed against Staphylococcus aureus, Escherishia coli, Pseudomonas aeruginosa, and Candida albicans using agar well diffusion method and concentration range of 500-3000mg/mL. Results of the chemical analysis of G. glabra root extracts proved that the aqueous extract contained saponin, flavonoids, glycosides, but lacked alkaloids and phenols. The ethanolic extract contained tannins and terpenoids. All tested isolates were sensitive to both extracts at concentration of 3000 mg/ml. S. aureus and E. coli showed higher sensitivity, maximum effective inhibition for G. glabra aqueous extract was found against S.aureus, whereby the minimum inhibition was recorded against P. aeruginosa. Regarding G. glabra alcoholic extracts, the highest effect was noticed against P. aeruginosa, while the lowest effect was noticed on C.albicans.
Keywords
Glycyrrhiza glabra; roots; chemical analysis; antimicrobial activity
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