25-HYDROXY VITAMIN D SERUM LEVEL IN CHILDREN WITH CONGENITAL HEART DISEASE | ||||
| Benha Medical Journal | ||||
| Article 262, Volume 39, Issue 2, July and August 2022, Page 602-610 PDF (517.58 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/bmfj.2022.126498.1557 | ||||
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| Authors | ||||
Eman G. Abdel Rahman 1; Soha El-Gendi2; waleed abdellateef3; Mohamed Sami Attia  4
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| 1Lecturer of Pediatrics Faculty of Medicine - Benha University | ||||
| 2Department of Paediatrics-Faculty of Mediicine-Benha University | ||||
| 3department of clinical and chemical pathology faculty of medicine benha university | ||||
| 4MBBCH | ||||
| Abstract | ||||
| Background & Aim: Identification of 25(OH) Vit D receptors in endothelial cells, smooth muscle cells, and myocytes from the heart has led to the hypothesis that this 25(OH) Vit D is involved in cardiovascular disease. The present study was designed to evaluate 25-hydroxy Vitamin D serum levels in congenital heart disease (CHD) children compared to controls. Methods: This case control study included 100 children, divided into 2 groups, Group (A) included 60 children with CHD who were divided into two groups (cyanotic and acyanotic). And group (B) included 40 apparently healthy children as a control group. All patients included in the study were subjected to the following: complete history taking and physical examination, echocardiography, and serum 25 (OH) vitamin D levels. Results: The mean serum.25 (OH) vitamin D level was significant lower in the CHD group than control group . the Serum.25 (OH) vitamin D level was significant lower in cyanotic group than acyanotic patients . there were a statistically significant difference between Serum.25 (OH) vitamin D level with various age groups of cyanotic and acyanotic patients. Conclusion: The serum level of 25(OH) Vit D was lower in CHD children, and among the patients, was lower in cyanotic. So it should be checked in CHD children especially those who suffered from cyanotic heart disease. | ||||
| Keywords | ||||
| Vitamin D; Congenital; Heart; CHD; Children | ||||
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