PRODUCTION AND EVALUATION OF A COMBINED INACTIVATED VACCINE AGAINST FOOT AND MOUTH DISEASE AND RIFT VALLEY FEVER USING ISA25 OIL ADJUVANT | ||||
| Egyptian Journal of Agricultural Research | ||||
| Article 35, Volume 83, Issue 1, March 2005, Page 439-449 PDF (2.38 MB) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ejar.2005.243342 | ||||
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| Authors | ||||
| SAMER M. ALI; TAUMOR N. MARCOSS | ||||
| Veterinary Serum and Vaccine Research Institute, Agricultural Research Centre, Ministry of Agriculture, Dokki, Giza, Egypt | ||||
| Abstract | ||||
| As a way to safe time, cost and reduction of stress on the vaccinated animals, a combined vaccine was formulated to contain FMD (0J93 Aga) strain and RVF (211501) strain , The vaccine was inactivated by binary ethylenemine (BEI) and adjuvanted with a Montanide ISA25 oil adjuvant. A comparison was held between the results of combined vaccine and FMD and RVF vaccines separately. Both single vaccines were inactivated and adjuvanted as the combined one. The achieved results indicated that the combined FMD/RVF vaccine appeared to be more potent and slightly increased in antibody titer than monovalent either RID or RVF vaccine. The antibody titers measured for 40 weeks post vaccination in the three used vaccines as measured by different serological techniques. At the same time, the two viruses did not interfere with each other. | ||||
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