Detection of Antimicrobial Resistance Genes in Children Suffering from HelicobacterPylori Infection | ||||
| Benha Journal of Applied Sciences | ||||
| Article 27, Volume 7, Issue 5, May 2022, Page 179-186 PDF (429.76 K) | ||||
| Document Type: Original Research Papers | ||||
| DOI: 10.21608/bjas.2022.244769 | ||||
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| Authors | ||||
| E.A. Elzaher; M.S. EL-Defrawy; N.F. Elhosiny; O.G. Behairy | ||||
| Pediatrics, Dept., Faculty of Medicine, Benha Univ., Benha, Egypt | ||||
| Abstract | ||||
| Background: Adult populations across the globe have an infection rate of H. pylori ranging from 20% to 90%. In Western communities, infection rates vary from 30 percent to 60 percent; in Asian nations and poor countries, the rates might be as high as 90 percent. H. pylori infection was found in the stomachs of 72.38 percent of Egyptian students. According to reports, the incidence of H. pylori infections in Egypt ranges from 70 to 88 percent in patients with chronic active HCV infection, depending on the type of infection. The bacteria is typically passed on via bloodlines and is most often picked up as a youngster. Chronic gastritis, peptic ulcer, and gastric cancer may all occur from a lack of therapy for gas trick colonisation. It is our goal to: Antimicrobial resistance genes (metronidazole, amoxicillin, clarithromycin) in children with Helicobacter pylori infection are the focus of this investigation. An Upper Gastrointestinal Endoscopy or gastroscopy was performed on 20 children aged less than 18 years old who complained of recurring stomach discomfort and were found to have a positive test for Helicobacter Pylori infection over the course of this prospective investigation. Banha University Hospital's department of paediatrics is where the research is taking place (Hepatology and Gastroenterology clinic). A structured interview was used to gather information on the patient's age, sex, gender identity, location, onset and duration of abdominal pain as well as any other symptoms that may be associated with H. pylori infection, such as epigastric pain and vomiting, dyspepsia, and gastrointestinal bleeding. Results: There were a total of 20 patients who were randomly chosen to participate in the research. Weight 42, Height 147.2 BMI 19, BMI (Centile) 56,36 and BMI (Control) 12.10 were the averages for the Control Group, whereas for the Experimental Group, the averages were 12.7 BMI (Centile), 45.5 BMI, Height 148.5 BMI (19.24 BMI) and 66.86 BMI (Centile). The percentage of (symptoms associated with H. pylori infection) and (symptoms in the case of the control group) the percentage of Abdominal pain before meal 100%, Abdominal pain relieved by food 0%, Pain relieved by antacid 80%, Night pain 70%, Nausea 80%, Vomiting 60%, Pain aggravated by food 100%, Pain relieved by belching 30%, Abdominal distension 20%, Anorexia & Weight loss 60%, Heart burn 80% Symptoms in the Experimental group include 100% of the subjects reporting abdominal pain before meals, 0% reporting relief from abdominal pain after meals, 100% reporting pain relief from antacids, 90% reporting night pain, 80% reporting nausea, 50% reporting vomiting, 100% reporting pain aggravated by food, 20% reporting pain relief from belching, 10% reporting abdominal distension, 50% reporting anorexia and weight loss, 70% reporting heart burn, 40% reporting chest pain, and 40% reporting GIT blee. | ||||
| Keywords | ||||
| Antimicrobial; Resistance Genes; Children; Helicobacter Pylori | ||||
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