Biologically Active Saponins of Genus Cestrum L.: A Comprehensive Review
Bahgat, D., Gad, H., Elsayed, E., Eldahshan, O., Singab, A. (2022). Biologically Active Saponins of Genus Cestrum L.: A Comprehensive Review. EKB Journal Management System, 6(1), 98-113. doi: 10.21608/aps.2022.129734.1085
Dina M Bahgat; Haidy A. Gad; Eman Elsayed; Omayma A. Eldahshan; Abdel-Nasser Singab. "Biologically Active Saponins of Genus Cestrum L.: A Comprehensive Review". EKB Journal Management System, 6, 1, 2022, 98-113. doi: 10.21608/aps.2022.129734.1085
Bahgat, D., Gad, H., Elsayed, E., Eldahshan, O., Singab, A. (2022). 'Biologically Active Saponins of Genus Cestrum L.: A Comprehensive Review', EKB Journal Management System, 6(1), pp. 98-113. doi: 10.21608/aps.2022.129734.1085
Bahgat, D., Gad, H., Elsayed, E., Eldahshan, O., Singab, A. Biologically Active Saponins of Genus Cestrum L.: A Comprehensive Review. EKB Journal Management System, 2022; 6(1): 98-113. doi: 10.21608/aps.2022.129734.1085

Biologically Active Saponins of Genus Cestrum L.: A Comprehensive Review

Archives of Pharmaceutical Sciences Ain Shams University
Article 9, Volume 6, Issue 1, June 2022, Page 98-113  XML PDF (590.25 K)
Document Type: Review Article
DOI: 10.21608/aps.2022.129734.1085
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Authors
Dina M Bahgat1; Haidy A. Gad2; Eman Elsayedorcid 3; Omayma A. Eldahshan email orcid 4; Abdel-Nasser Singab email 2
1Department of Pharmacognosy, Faculty of Pharmacy, Ain Shams University, Cairo 11566, Egypt
2Department of Pharmacognosy, Faculty of Pharmacy, Ain Shams University, Abbassia, Cairo 11566, Egypt
3Department of Pharmacognosy, Faculty of Pharmacy, Ain-Shams University, Cairo, Egypt
4Pharmacognosy Department, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt.
Abstract
Abstract
Genus Cestrum L. belonging to family Solanaceae comprises from 250 to 300 species of flowering plants that are native to warm temperate to tropical regions of America. Shrubs of Cestrum L. species are known as Jessamines due to their highly fragrant flowers. They are planted not only for their ornamental uses but also for their valuable and diverse medicinal effects. In many African, Asian and American countries, folk medicine practitioners use different Cestrum L. species for their important ethno- pharmacological effects and diverse biological properties. In the last decades, fifty-two saponins; mainly of steroidal nucleus; have been isolated and identified form certain Cestrum L. species and they were responsible for numerous important biological activities as cytotoxic activity, pesticidal activity spermicidal activity, anti-microbial activity and anti-inflammatory effect. In this updated review till 2021, we highlighted the pharmacological importance of those steroidal saponins, their biosynthetic pathway and the relation between the chemical structure and biological activity.
Keywords
Cestrum; steroidal saponins; cytotoxic activity; pesticidal activity; biosynthesis
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