Evaluation of growth-promoting effects of silver nanoparticles and magnetic water in broilers | ||||
| Suez Canal Veterinary Medical Journal. SCVMJ | ||||
| Articles in Press, Accepted Manuscript, Available Online from 30 June 2022 | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/scvmj.2022.140052.1081 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Abeer Hassanin   1; Ahmed Elaswad1; Karim Khalil2; Walaa Husseiny3; Adel Ahmed sabry Elnabtiti4
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| 1Department of Animal Wealth Development, Faculty of Veterinary Medicine, Suez Canal University, Ismailia, Egypt | ||||
| 2Anatomy and Embryology Department, Faculty of Veterinary Medicine, Cairo University, Giza , Egypt | ||||
| 3Department of Animal Wealth Development, Faculty of Veterinary Medicine, Suez Canal University, Ismailia , Egypt | ||||
| 4Animal Wealth Development, Faculty of veterinary Medicine, Suez Canal University, Ismailia , Egypt | ||||
| Abstract | ||||
| Previously, we assessed the effects of silver nanoparticles (Nano-Ag) on myogenesis-related gene expression during chicken embryogenesis, where the injection of 20 ppm of Nano-Ag resulted in gene expression alterations accompanied by hyperplasia of skeletal muscle fibers. We conducted the current study to furtherly investigate the effect of Nano-Ag on the post-hatch expression of myogenesis-related genes and its reflection on muscle development and productive performance of birds. Nano-Ag were administered in normal or magnetic water for 35 days. Productive performance parameters such as body weight (BW), body weight gain (BWG), feed intake (FI), feed conversion ratio (FCR), and European production efficiency factor (EPEF) were investigated. Expression of selected myogenesis-related genes was assessed at the mRNA and protein levels, and breast muscle development was also investigated. The results indicated no effect of Nano-Ag and magnetic water on BWG and FI. However, the lowest FCR and the highest EPEF and BW were recorded in the group in ovo injected with 20 ppm Nano-Ag and received 20 ppm Nano-Ag in magnetic water. In ovo injection of 40 ppm Nano-Ag followed by post-hatch administration of 40 ppm Nano-Ag in normal water increased the expression of myogenic determination factor 1 (MYOD1) mRNA and protein in breast muscles by 4.0 and 1.8 folds, respectively, and resulted in 19.9% more muscle fibers than the control group. Magnetic water alone increased the gene expression at the mRNA level but not at the protein level and decreased the number of muscle fibers by 26.47% than the control group. Nano-Ag in combination with magnetic water is a committed growth-promoting agent in broiler production at a low dose. | ||||
| Keywords | ||||
| Silver nanoparticles; Broiler production; Magnetic water; MRFs; Productive performance | ||||
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