Bacterial Profile and Antibiotics Susceptibility Pattern of Pleural Effusion Isolates from Sohag University Hospital | ||||
Egyptian Journal of Medical Microbiology | ||||
Volume 31, Issue 3, July 2022, Page 29-35 PDF (337.74 K) | ||||
Document Type: New and original researches in the field of Microbiology. | ||||
DOI: 10.21608/ejmm.2022.247177 | ||||
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Authors | ||||
Ashraf Khodeary1; Tamer Mohamed 2; Khaled Alkhayat3; Sherif Sayed4 | ||||
1Clinical Pathology Department, Faculty of Medicine, Sohag University, Egypt | ||||
2Medical Microbiology and Immunology department, Faculty of Medicine, Sohag University, Sohag , Egypt | ||||
3Chest Department, Faculty of Medicine, Sohag University, Egypt | ||||
4Lecturer, Clinical Pathology Department, Faculty of Medicine, Sohag University, Egypt | ||||
Abstract | ||||
Background: Diagnosis of pleural effusion (PE) infection and the isolated organisms reported a significant resistance to the commonly used antibiotics, and the choice of appropriate antibiotics for the management should be guided by microbiological results. Objectives: This study aimed to detect the bacterial profile and antibiotics susceptibility pattern of PE isolates and the prevalence of methicillin-resistant Staph. aureus. Methodology: Plural fluid samples from 121 patients with PE infection were collected for microbiological identification and antibiotic sensitivity testing by Vitek 2 system, Staphylococcal aureus isolates were tested for MecA gene by RT-PCR. Results: 47% of PE samples exhibited positive culture, the most encountered organisms were Staph. aureus (24.2%), Klebsiella pneumoniae (16.1%), Staph aureus had the highest sensitivity to Vancomycin and Linezolid (100%) and (40%) of Staph aureus had mecA gene. Conclusion: Bacteria isolated from PE exhibited increasing levels of antibiotic resistance that should be reflected in the choice of empirical antimicrobial treatment. | ||||
Keywords | ||||
Bacterial isolates; Antibiotic resistance; Pleural Fluid | ||||
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