Predictive values of first trimester ultrasound screening for twin-to-twin transfusion syndrome and selective intrauterine growth restriction in monochorionic twin pregnancies
Ali, A., Mostafa, A., Hussein, M., Khodry, M. (2022). Predictive values of first trimester ultrasound screening for twin-to-twin transfusion syndrome and selective intrauterine growth restriction in monochorionic twin pregnancies. EKB Journal Management System, 5(2), 329-335. doi: 10.21608/svuijm.2022.136000.1305
Abd El-Naser Abd El-Gaber Ali; Altayeb Abd-alal Mostafa; Mostafa Hussein; Mostafa Mohammad Khodry. "Predictive values of first trimester ultrasound screening for twin-to-twin transfusion syndrome and selective intrauterine growth restriction in monochorionic twin pregnancies". EKB Journal Management System, 5, 2, 2022, 329-335. doi: 10.21608/svuijm.2022.136000.1305
Ali, A., Mostafa, A., Hussein, M., Khodry, M. (2022). 'Predictive values of first trimester ultrasound screening for twin-to-twin transfusion syndrome and selective intrauterine growth restriction in monochorionic twin pregnancies', EKB Journal Management System, 5(2), pp. 329-335. doi: 10.21608/svuijm.2022.136000.1305
Ali, A., Mostafa, A., Hussein, M., Khodry, M. Predictive values of first trimester ultrasound screening for twin-to-twin transfusion syndrome and selective intrauterine growth restriction in monochorionic twin pregnancies. EKB Journal Management System, 2022; 5(2): 329-335. doi: 10.21608/svuijm.2022.136000.1305

Predictive values of first trimester ultrasound screening for twin-to-twin transfusion syndrome and selective intrauterine growth restriction in monochorionic twin pregnancies

SVU-International Journal of Medical Sciences
Article 32, Volume 5, Issue 2, July 2022, Page 329-335  XML PDF (201.08 K)
Document Type: Original research articles
DOI: 10.21608/svuijm.2022.136000.1305
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Authors
Abd El-Naser Abd El-Gaber Ali1; Altayeb Abd-alal Mostafa email 1; Mostafa Hussein2; Mostafa Mohammad Khodry1
1Department of Obstetrics and Gynecology, Faculty of Medicine, South Valley University, Qena, Egypt.
2Department of Obstetrics and Gynecology, Faculty of Medicine, Assiut University, Assiut, Egypt.
Abstract
Background: Monochorionic diamniotic (MCDA) twins have a substantially higher risk for perinatal morbidity and mortality due to the presence of placental vascular anastomoses between the twins.
Objectives: The primary purpose of this research was to confirm the accuracy of first trimester ultrasonography in predicting selective intrauterine growth restriction (SIGR) and twin-to-twin transfusion syndrome (TTTS) in monochorionic twin pregnancies using the triad of nuchal translucency (NT), cord insertion and inter-twin discordance in foetal size.
Patients and methods: This was a prospective cohort study that included 31 pregnant women who were carrying monochorionic twins during the first trimester. The research was carried out at a foetal medicine unite, Obstetrics and Gynecology Department, South Valley University Hospital. The duration of the study ranged from 18 to 24 months.
Results: the mean difference in NT can determine TTTS with fair sensitivity (73.2%) and high specificity (100%) in twins (p < 0.001). Likewise, mean difference in CRL can determine TTTS with fair sensitivity (73.1%) and high specificity (100%) in twins (p < 0.001).The mean difference in NT can determine sIUGR with high sensitivity (100%) and fair specificity (73.2%) in twins (p < 0.001). Likewise, mean difference in CRL can determine sIUGR with high sensitivity (100%) and fair specificity (73.1%) in twins (p < 0.001).
Conclusion: we have demonstrated that NT and CRL were significantly higher in TTTS group, and NT and CRL were respectively identified as the predictive markers for sIUGR and TTTS.
Keywords
monochorionic twin pregnancies; sIUGR; perinatal morbidity
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