PLASMA PROTEINS PROFILE IN NILE TILAPIA (OREOCHROMIS NILOTICUS) AND COMMON CARP (CYPRINUS CARPIO) EXPOSED TO OCHRATOXIN- A AND TREATED WITH SOME ANTITOXINS | ||||
| Egyptian Journal of Agricultural Research | ||||
| Article 26, Volume 83, Issue 3, September 2005, Page 1397-1416 PDF (3.5 MB) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ejar.2005.247852 | ||||
 View on SCiNiTO | ||||
| Author | ||||
| MOHAMED E. FARAG | ||||
| Central Laboratory for Aquaculture Research, Abbassa, Agricultural Research center, Ministry of Agriculture, Dokki, Giza, Egypt | ||||
| Abstract | ||||
| This study was carried out to investigate the ability of minimum level (0.5%) (Tri star, Mycoband and Mould Stop Super) to resist the toxicity of Ochratoxin A (7mg 0.A/ Kg diet). The growth parameters and protein fractionation in Oreochromis nlloticus and Cyprinus carpio were recorded. Five groups of apparently healthy fish with mean body weight of 50-60 g for Oreochromis niloticus-, and fingerlings with a mean body weight of 9-11 g for Cyprinus carpio were used. Ochratoxin A caused loss in live body weight gains in Oreochromis niloticus and Cyprinus carpio. Addition of the adsorbents reduced the had effects of Ochratoxin A on growth performance (Live body weight, body weight gain and specific growth rate). Concurred the electrophoretic investigation, plasma protein of fish showed the presence of 22-24 and 18 main fractions in control group of the various sera of Oreochromis niloticus and Cyprinus carpi°, respectively. The genotoxic effects of ochratoxin A led to a loss of two bands at mobility 0.01 & 0.135, while, new fraction appeared at mobility 0.96 in Orcochromis nilottus. Also, new fractions appeared at mobility 0.059, 0.089, 0.774 & 0.904 in Cyprinus carpi°. Addition of 0.5% adsorbents (Tri star, mycoband and Mould Stop Super) on contaminated diet with 7 mg ochratoxin A /kg led to appearance of new bands at mobility 0.01, 0.135 & 0.539 in 0. niloticus, and at mobility 0.281 & 0.824 in Cyprinus carpio as control group. It is concluded that the adsorbents were able to resist the toxicity of Ochratoxin A and to improve the growth parameters and plasma protein in fish. | ||||
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