Magnesium Sulphate Versus Dexmedetomidine for Prevention of Emergence Agitation (EA) after Sevoflurane in Adult Patients Undergoing Percutaneous Nephrolithotomy
Ahmed, A., Mohammed, M., Alsagheer, G., Ismail, M. (2022). Magnesium Sulphate Versus Dexmedetomidine for Prevention of Emergence Agitation (EA) after Sevoflurane in Adult Patients Undergoing Percutaneous Nephrolithotomy. EKB Journal Management System, 88(1), 3434-3438. doi: 10.21608/ejhm.2022.248722
Abbady Abdellah Ahmed; Mohammed Hussam El-din Mohammed; Gamal A. Alsagheer; Mahmoud Mohammed Ahmed Ismail. "Magnesium Sulphate Versus Dexmedetomidine for Prevention of Emergence Agitation (EA) after Sevoflurane in Adult Patients Undergoing Percutaneous Nephrolithotomy". EKB Journal Management System, 88, 1, 2022, 3434-3438. doi: 10.21608/ejhm.2022.248722
Ahmed, A., Mohammed, M., Alsagheer, G., Ismail, M. (2022). 'Magnesium Sulphate Versus Dexmedetomidine for Prevention of Emergence Agitation (EA) after Sevoflurane in Adult Patients Undergoing Percutaneous Nephrolithotomy', EKB Journal Management System, 88(1), pp. 3434-3438. doi: 10.21608/ejhm.2022.248722
Ahmed, A., Mohammed, M., Alsagheer, G., Ismail, M. Magnesium Sulphate Versus Dexmedetomidine for Prevention of Emergence Agitation (EA) after Sevoflurane in Adult Patients Undergoing Percutaneous Nephrolithotomy. EKB Journal Management System, 2022; 88(1): 3434-3438. doi: 10.21608/ejhm.2022.248722

Magnesium Sulphate Versus Dexmedetomidine for Prevention of Emergence Agitation (EA) after Sevoflurane in Adult Patients Undergoing Percutaneous Nephrolithotomy

The Egyptian Journal of Hospital Medicine
Article 185, Volume 88, Issue 1, July 2022, Page 3434-3438  XML PDF (344.83 K)
DOI: 10.21608/ejhm.2022.248722
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Authors
Abbady Abdellah Ahmed1; Mohammed Hussam El-din Mohammed1; Gamal A. Alsagheer2; Mahmoud Mohammed Ahmed Ismail* 1
1Departments of 1Anaesthesia and Surgical ICU
22Urology, Faculty of Medicine, South Valley University, Qena, Egypt.
Abstract
Background: The utilization of sevoflurane as inhalational agent may cause emergence agitation (EA)during recovery from general anesthesia. EA has also been specified to emergence delirium, and sometimes it is accompanied with negative postoperative behaviors. The aim of this study was to compare the effect of magnesium sulphate and dexmedetomidine infusion on prevention of EA after sevoflurane anesthesia in adult patients undergoing percutaneous nephrolithotomy (PCNL).
Patients and methods: This study was carried out at Anaesthesia, Intensive Care Unit and Pain Management Department, Qena university Hospital on 50 adult patients undergoing PCNL under general anesthesia using sevoflurane as inhalational agent. Participants were divided into two groups: group I (25 patients) received initial intravenous magnesium sulphate and group II (25 patients) received dexmedetomidine infusion.
Results: There was statistically significant difference between both groups regarding Richmond Agitation Sedation Scale (RASS). The mean VAS was 7.2 (SD 1.9) and 2.6 (SD 0.9) among groups 1 and 2, respectively. There was statistically significant difference between both groups regarding VAS and hemodynamics
Conclusion: Intraoperative infusion of either dexmedetomidine or magnesium sulfate after sevoflurane in adult patients undergoing PCNL decreased postoperative agitation and pain intensity with the superiority of dexmedetomidine. However, the magnesium sulfate gives more hemodynamic stability, so it was preferred for patients with severe comorbidities.
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