Leukocyte-Platelet Rich Fibrin (L-PRF) and L-PRF mixed with particulate xenograft as alveolar ridge preservation materials after extraction of teeth with chronic periapical infection (A randomized controlled clinical study with radiographic and histomorphometrical assessment)
El Guindy, S., Kheir El Din, N., Masloub, S., AMR, A. (2022). Leukocyte-Platelet Rich Fibrin (L-PRF) and L-PRF mixed with particulate xenograft as alveolar ridge preservation materials after extraction of teeth with chronic periapical infection (A randomized controlled clinical study with radiographic and histomorphometrical assessment). EKB Journal Management System, 68(3), 2235-2253. doi: 10.21608/edj.2022.126866.2018
sherif El Guindy; Nevine Kheir El Din; Shaimaa Masloub; AHMED AMR. "Leukocyte-Platelet Rich Fibrin (L-PRF) and L-PRF mixed with particulate xenograft as alveolar ridge preservation materials after extraction of teeth with chronic periapical infection (A randomized controlled clinical study with radiographic and histomorphometrical assessment)". EKB Journal Management System, 68, 3, 2022, 2235-2253. doi: 10.21608/edj.2022.126866.2018
El Guindy, S., Kheir El Din, N., Masloub, S., AMR, A. (2022). 'Leukocyte-Platelet Rich Fibrin (L-PRF) and L-PRF mixed with particulate xenograft as alveolar ridge preservation materials after extraction of teeth with chronic periapical infection (A randomized controlled clinical study with radiographic and histomorphometrical assessment)', EKB Journal Management System, 68(3), pp. 2235-2253. doi: 10.21608/edj.2022.126866.2018
El Guindy, S., Kheir El Din, N., Masloub, S., AMR, A. Leukocyte-Platelet Rich Fibrin (L-PRF) and L-PRF mixed with particulate xenograft as alveolar ridge preservation materials after extraction of teeth with chronic periapical infection (A randomized controlled clinical study with radiographic and histomorphometrical assessment). EKB Journal Management System, 2022; 68(3): 2235-2253. doi: 10.21608/edj.2022.126866.2018

Leukocyte-Platelet Rich Fibrin (L-PRF) and L-PRF mixed with particulate xenograft as alveolar ridge preservation materials after extraction of teeth with chronic periapical infection (A randomized controlled clinical study with radiographic and histomorphometrical assessment)

Egyptian Dental Journal
Article 5, Volume 68, Issue 3, July 2022, Page 2235-2253  XML PDF (2.33 MB)
Document Type: Original Article
DOI: 10.21608/edj.2022.126866.2018
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Authors
sherif El Guindyorcid 1; Nevine Kheir El Dinorcid 2; Shaimaa Maslouborcid 3; AHMED AMR email orcid 4
1Msc Periodontology Ain Shams University
2Professor of Oral Medicine, Periodontology and Oral Diagnosis, Faculty of Dentistry, Ain Shams University
3Lecturer at Oral Pathology Department, Faculty of Dentistry Ain Shams University
4Associate Professor of Oral Medicine and Periodontology Faculty of Dentistry Ain Shams University
Abstract
Aim: The present study was performed to evaluate the use of L-PRF and L-PRF mixed with particulate xenograft as alveolar ridge preservation materials after extraction of a tooth with chronic infection. Evaluation of the buccolingual dimensional changes of alveolar ridge was the primary objective while the secondary objectives were evaluation of the quality of regenerated bone histomorphometrically and assessment of implant stability.

Subjects and methods: This is a randomized controlled clinical trial in which thirty patients were randomly distributed into three groups. Group 1: Ten extraction sockets where alveolar ridge preservation was performed using L-PRF plug. Group 2: Ten extraction sockets where alveolar ridge preservation was performed using L-PRF mixed with particulate xenograft. Group 3: Ten extraction sockets where alveolar ridge preservation was performed using xenograft and collagen membrane. Evaluation of the alveolar ridge dimensional changes was performed radiographically. Histological and histomorphometrical assessment of the regenerated bone was also performed.

Results: Regarding alveolar ridge buccolingual changes radiographically , The highest mean percent decrease was recorded in L-PRF group with the least value recorded in L-PRF mixed with xenograft group. Regarding the Area fraction of newly formed bone and osteocytes count , The highest mean value was recorded in L-PRF mixed with xenograft group with the least value recorded in L-PRF group.

Conclusion: L-PRF mixed with xenograft group showed better dimensional and histological outcomes in alveolar ridge preservation in comparison to L-PRF alone or xenograft and collagen membrane.
Keywords
L-PRF; Alveolar ridge preservation; xenografts; platelets concentrates
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