Preparation and characterization of a bioactive glass/agarose/gelatin nanocomposite scaffold for bone engineering
Ahmed, M., Ibrahim, A., Abd El-Hadya, B., Ali, A., El-kadya, A. (2015). Preparation and characterization of a bioactive glass/agarose/gelatin nanocomposite scaffold for bone engineering. EKB Journal Management System, 32(part 2), 153-168. doi: 10.21608/jsrs.2015.24905
Manar M. Ahmed; A. M. Ibrahim; Bothaina M. Abd El-Hadya; Ashraf F. Ali; Abeer M. El-kadya. "Preparation and characterization of a bioactive glass/agarose/gelatin nanocomposite scaffold for bone engineering". EKB Journal Management System, 32, part 2, 2015, 153-168. doi: 10.21608/jsrs.2015.24905
Ahmed, M., Ibrahim, A., Abd El-Hadya, B., Ali, A., El-kadya, A. (2015). 'Preparation and characterization of a bioactive glass/agarose/gelatin nanocomposite scaffold for bone engineering', EKB Journal Management System, 32(part 2), pp. 153-168. doi: 10.21608/jsrs.2015.24905
Ahmed, M., Ibrahim, A., Abd El-Hadya, B., Ali, A., El-kadya, A. Preparation and characterization of a bioactive glass/agarose/gelatin nanocomposite scaffold for bone engineering. EKB Journal Management System, 2015; 32(part 2): 153-168. doi: 10.21608/jsrs.2015.24905

Preparation and characterization of a bioactive glass/agarose/gelatin nanocomposite scaffold for bone engineering

Journal of Scientific Research in Science
Article 27, Volume 32, part 2, November 2015, Page 153-168  XML PDF (763.02 K)
Document Type: Original Article
DOI: 10.21608/jsrs.2015.24905
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Authors
Manar M. Ahmed email 1; A. M. Ibrahim2; Bothaina M. Abd El-Hadya1; Ashraf F. Ali3; Abeer M. El-kadya1
1Biomaterials Department, National Research Center, 33 El-Behooth St., Dokki, Giza, Egypt
2Physics Departement, University Collage of Women (Arts, Science, and Education), Ain-Shams University
3Inorganic Chemistry Department, National Research Center, 33 El-Bohooth St., Dokki 12622, Cairo, Egypt
Abstract
A bioactive glass/agarose/gelatin nanocomposite scaffold was prepared for bone engineering application. The scaffold was characterized by Scaning Electron Microscopy (SEM), Fourier infrared spectra (FTIR), andThermogravimetric Aanalysis(TGA). SEM micrographs showed that the scaffold had a well-interconnected macroporous structure. TGA indicated that the glass content in the scaffold was 57.12% which is close to the predecided one (60 wt%). The porosity percentage of the scaffold was measured by mercury porosimetry which showed that the scaffold has high porosity percentage (71.30%). In vitro bioactivity evaluation was carried out by immersion of the scaffold in simulated body fluid (SBF) for 2 and 4 weeks. Results showed that the scaffold was able to induce an apatite layer on its surface as verified by SEM, FTIR and Thin Film X-ray (TXRD).
 
 
Keywords
Biocomposites; agarose and gelatin; biodegradation; bone treatment
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