THE HISTOPATHOLOGICAL EFFECTS OF WARFARIN AND CHLOROPHACINONE ANTICOAGULANT RODENTICIDES ON MALE ALBINO RATS | ||||
| Journal of Plant Protection and Pathology | ||||
| Article 3, Volume 28, Issue 7, July 2003, Page 5685-5698 PDF (1.53 MB) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/jppp.2003.251421 | ||||
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| Authors | ||||
| H. I. EI-Deeb; W. M. Gabr; Fatma K. Khidr; E. A. EI-Essely | ||||
| Plant Protection Research Institute, Agr. Res. Center, Dokki - Giza. | ||||
| Abstract | ||||
| The hislopathological effects of warfarin and chlorophacinone anticoagulant rodenticides were studied on liver. kidney and testis of male albino rats Rattus nONegicus after administration of sub - lethal doses (1/10and 'I. LD!o) after 15 days post - treatment. The microscopical examination showed that there were injuries in these organs depending on the dose level. In liver. both tested compounds induced dilation of central and portal vein. congestion with lymphocytic infiltration and necrosis. In kidney , the two tested compounds occurred renal cloudy swelling. congestion. lymphocytic infiltration, focal areas of haemorrhage in the internal tubular connective tissues and necrosis. Also, the effect of the two compounds on the testis showed that there were thickness basement membrane and lymphocytic infiltration of seminiferous tubules. | ||||
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