Role of Human Coronaviruses in Acute Respiratory Infections and Seroprevalence of Middle East Respiratory Syndrome Coronavirus in children
Fahmy, G., Erfan, D., Magdy, S., Hassan, R. (2020). Role of Human Coronaviruses in Acute Respiratory Infections and Seroprevalence of Middle East Respiratory Syndrome Coronavirus in children. EKB Journal Management System, 29(4), 65-73. doi: DOI:https://doi.org/10.51429/EJMM29409
Ghada A. Fahmy; Dina M. Erfan; Sondos M. Magdy; Rania A. Hassan. "Role of Human Coronaviruses in Acute Respiratory Infections and Seroprevalence of Middle East Respiratory Syndrome Coronavirus in children". EKB Journal Management System, 29, 4, 2020, 65-73. doi: DOI:https://doi.org/10.51429/EJMM29409
Fahmy, G., Erfan, D., Magdy, S., Hassan, R. (2020). 'Role of Human Coronaviruses in Acute Respiratory Infections and Seroprevalence of Middle East Respiratory Syndrome Coronavirus in children', EKB Journal Management System, 29(4), pp. 65-73. doi: DOI:https://doi.org/10.51429/EJMM29409
Fahmy, G., Erfan, D., Magdy, S., Hassan, R. Role of Human Coronaviruses in Acute Respiratory Infections and Seroprevalence of Middle East Respiratory Syndrome Coronavirus in children. EKB Journal Management System, 2020; 29(4): 65-73. doi: DOI:https://doi.org/10.51429/EJMM29409

Role of Human Coronaviruses in Acute Respiratory Infections and Seroprevalence of Middle East Respiratory Syndrome Coronavirus in children

Egyptian Journal of Medical Microbiology
Volume 29, Issue 4, October 2020, Page 65-73  XML PDF (422.46 K)
Document Type: New and original researches in the field of Microbiology.
DOI: DOI:https://doi.org/10.51429/EJMM29409
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Authors
Ghada A. Fahmy* 1; Dina M. Erfanorcid 1; Sondos M. Magdy2; Rania A. Hassan1
1Department of Medical Microbiology and Immunology, Faculty of Medicine-Ain Shams University
2Department of Pediatrics, Faculty of Medicine-Ain Shams University
Abstract
Background: Coronaviruses have been the focus of many studies since the emergence of SARS-CoV. Data on the role of MERS-CoV in respiratory tract infection and the seroprevalence of MERS-CoV in Egypt are limited. Objective: This study aimed to determine the role of coronaviruses in respiratory tract infections and the seroprevalence of MERS-CoV in pediatric age group. Methodology: Respiratory samples were collected from 80 children with respiratory infections for detection of coronaviruses using PCR technique. Serum samples were collected from 200 children for detection of MERS-CoV IgG immunolglobulins. Results: 4 out of 80 (5%) of the respiratory samples tested positive for coronavirus (OC43 subtype). None of respiratory samples tested positive for MERS-CoV, while MERS-CoV IgG was detected in 1% of serum samples.Conclusion: A low prevalence of coronaviruses was observed in children with respiratory infection. A seroprevalence of 1% MERS-CoV was detected. Further studies are recommended on larger scale.
Keywords
Coronaviruses; MERS-CoV; viral respiratory infection
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