Biochemical changes in Egyptian patients infected with COVID-19
El-Adly, A., Wardany, A., Shikhoun, M. (2022). Biochemical changes in Egyptian patients infected with COVID-19. EKB Journal Management System, 8(3), 143-153. doi: 10.21608/jbaar.2022.251729
Ahmed M. El-Adly; Ahmed A. Wardany; Mohey H. Shikhoun. "Biochemical changes in Egyptian patients infected with COVID-19". EKB Journal Management System, 8, 3, 2022, 143-153. doi: 10.21608/jbaar.2022.251729
El-Adly, A., Wardany, A., Shikhoun, M. (2022). 'Biochemical changes in Egyptian patients infected with COVID-19', EKB Journal Management System, 8(3), pp. 143-153. doi: 10.21608/jbaar.2022.251729
El-Adly, A., Wardany, A., Shikhoun, M. Biochemical changes in Egyptian patients infected with COVID-19. EKB Journal Management System, 2022; 8(3): 143-153. doi: 10.21608/jbaar.2022.251729

Biochemical changes in Egyptian patients infected with COVID-19

Journal of Bioscience and Applied Research
Volume 8, Issue 3, September 2022, Page 143-153  XML PDF (1.13 MB)
Document Type: Original Article
DOI: 10.21608/jbaar.2022.251729
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Authors
Ahmed M. El-Adly email 1; Ahmed A. Wardany1; Mohey H. Shikhoun2
1Botany and Microbiology Department, Faculty of Science, Al-Azhar University, 71524Assiut Branch, Egypt
2Analysis and Laboratories Department, Higher Technological Institute of Applied Health Sciences in Sohag, Ministry of Higher Education, Cairo, Egypt
Abstract
A pandemic-scale outbreak of the newly discovered coronavirus disease 2019 (COVID-19), fast-spreading viral pneumonia, is currently occurring. Due to the disease's overall vulnerability, different age groups have different clinical characteristics and test findings. The purpose of this study was to describe the COVID-19 laboratory results in various age and sex groups. Reverse transcriptase polymerase chain reaction (RT-PCR) for SARS-2 RNA was used in the study, which had 1100 individuals with typical cold symptoms. It was reported that 660 of these cases tested positive for the test, while 440 tested negative, therefore all cases underwent laboratory testing. Our research revealed that males had higher COVID-19 positivity than females (215/660; 67.4%), with males scoring 445/660; 32.6%). Age does not statistically differ between COVID-19 positive and negative cases. Hematological parameters in blood cells revealed that Lymphocytes differ significantly between COVID-19-infected and uninfected patients as these cells decline in the presence of COVID-19 infection. There are no significant differences in hemoglobin (Hgb percent), red blood cells (RBCs), total white blood cells (WBCS), basophils, neutrophils, monocytes, and eosinophils, as well as blood platelets (PLTS). Erythrocyte sedimentation rate (ESR) is unimportant, whereas COVID-19 infection increases ferritin and C-reactive proteins. 
Keywords
COVID-19; SARS-CoV-2; diagnosis; laboratory findings
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