Association Between Apelin and Nitrous Oxide with Essential Hypertensive Patient and their Relation toSex
Mahmoud kadry, Z., Mahmoud Ahmed, A., Khalifa Ahmed, A., Hafez Abdelall, A., Mahmoud Mohamed, S., Ahmed, A. (2022). Association Between Apelin and Nitrous Oxide with Essential Hypertensive Patient and their Relation toSex. EKB Journal Management System, 26(2), 19-24. doi: 10.21608/smj.2022.127203.1305
Zeinab Mahmoud kadry; Alaa Mahmoud Ahmed; Asmaa Khalifa Ahmed; Alshimaa Hafez Abdelall; Samira Mahmoud Mohamed; Ahmed Othman Ahmed. "Association Between Apelin and Nitrous Oxide with Essential Hypertensive Patient and their Relation toSex". EKB Journal Management System, 26, 2, 2022, 19-24. doi: 10.21608/smj.2022.127203.1305
Mahmoud kadry, Z., Mahmoud Ahmed, A., Khalifa Ahmed, A., Hafez Abdelall, A., Mahmoud Mohamed, S., Ahmed, A. (2022). 'Association Between Apelin and Nitrous Oxide with Essential Hypertensive Patient and their Relation toSex', EKB Journal Management System, 26(2), pp. 19-24. doi: 10.21608/smj.2022.127203.1305
Mahmoud kadry, Z., Mahmoud Ahmed, A., Khalifa Ahmed, A., Hafez Abdelall, A., Mahmoud Mohamed, S., Ahmed, A. Association Between Apelin and Nitrous Oxide with Essential Hypertensive Patient and their Relation toSex. EKB Journal Management System, 2022; 26(2): 19-24. doi: 10.21608/smj.2022.127203.1305

Association Between Apelin and Nitrous Oxide with Essential Hypertensive Patient and their Relation toSex

Sohag Medical Journal
Article 3, Volume 26, Issue 2, May 2022, Page 19-24  XML PDF (465.4 K)
Document Type: Original Article
DOI: 10.21608/smj.2022.127203.1305
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Authors
Zeinab Mahmoud kadry1; Alaa Mahmoud Ahmed2; Asmaa Khalifa Ahmed3; Alshimaa Hafez Abdelall1; Samira Mahmoud Mohamed4; Ahmed Othman Ahmed email orcid 5
1Department of Biochemistry, Faculty of Medicine Sohag University
2Department of Ophthalmology, Faculty of Medicine Sohag University
3Department of Rheumatology and Rehabilitation, Faculty of Medicine, Sohag University.
4Histology Department, Faculty of Medicine, Sohag University
5Internal Medicine, Faculty of Medicine , sohag university, sohag, egypt
Abstract
Apelin is a new multi - functional peptide that has already been linked to blood pressure and cardiac function modulation. It's hypothesised to play a role in hypertension and hypertensive heart disease development., Nitric oxide (NO) was recognized as an endogenous signaling molecule that modulates vascular compliance and organ perfusion via its powerful vasodilatory effects, hypertension, atherosclerosis, and chronic renal problems, are hypothesized to limit NO bioavailability, leading to disease progression. Our study aimed to know the role of apelin and nitric oxide in the pathogenesis of essential hypertension and correlate the levels of apelin to nitric oxide in both genders, A total number of 90 participants (70 hypertensive patients and 20 control) were enrolled, all participants underwent blood pressure, serum apelin and NO measurement, our results revealed decreased serum apelin levels in essential hypertensive patients, while serum NO was increased compared to controls with no significant gender difference.

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Keywords
Apelin; Nitic Oxide; Hypertension
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