Evaluation of Adipokines Among Children Infected with Some Protozoan Intestinal Parasites | ||||
| The Egyptian Journal of Hospital Medicine | ||||
| Article 263, Volume 88, Issue 1, July 2022, Page 3906-3910 PDF (432.53 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ejhm.2022.252830 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Lina Jamal Al-Ani; Harith Saeed Al-Warid 
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| Abstract | ||||
| Background: Adipokines are molecules produced by adipose tissue that have involvement in the body's energy/metabolic status and inflammation. It has recently been shown that there is a relationship between these molecules and infection with some intestinal parasites. Objectives: The current research aimed to assess the effect of Cryptosporidium and Giardia lamblia on adipokines. Patients and methods: This research was conducted in Baghdad from October 2021 to March 2022. The study included 56 children of both sexes, ranging in age from 2 to 15 years. The enrolled children were divided, according their stool examination, into infected by Giardia lamblia (n=21), infected by Cryptosporidium (n=23) and apparently healthy children (n=12). All participating children were subjected to some biometric measurements (body mass index (BMI), weight for age percentile and height for age percentile) and adipokines assessment (adiponectin, leptin and IL-6). Results: A significant increase(P˂0.05) in adiponectin and leptin were observed for Cryptosporidium and G. lamblia infections versus the control group. While significant decrease (P˂0.05)in IL- 6 were noticed for Cryptosporidium and G. lamblia infections compared to the control group. BMI, weight for age percentile and height for age percentile were not significantly related with each of adiponectin, leptin and IL-6 for infected patients and control groups. Conclusions: Leptin and adiponectin secretion, as well as nutrient absorption, can be interfered with by intestinal Cryptosporidium and G. lamblia. Their precise function in intestinal parasitosis requires further study. | ||||
| Keywords | ||||
| Adiponectin; Cryptosporidium; Giardia lamblia; IL-6; Leptin | ||||
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