Leptin in farm animals: Productive and reproductive effects

S., Hussein Y.; El-Koly, Maha A.; Tag El-Din, Hanan A.; Mansour, Mogeda K.

doi:10.21608/ejceh.2015.253710

	Leptin in farm animals: Productive and reproductive effects
Egyptian Journal of Chemistry and Environmental Health
Volume 1, Issue 1, November 2015, Page 588-612 PDF (864.17 K)
Document Type: Scientific and Research
DOI: 10.21608/ejceh.2015.253710
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Authors
Hussein Y. S.^* ¹; Maha A. El-Koly²; Hanan A. Tag El-Din²; Mogeda K. Mansour²
¹Biotechnology Research Department, Animal Production Research Institute, Dokki, Giza
²Biochemistry,Toxicol & Feed deff. Department, Animal Health Research Institute, Dokki, Giza
Abstract
The ob factor, Leptin, produced from white adipose tissue is classified as a “metabolism modifier” or lipostat” or “adipostat” and it have myriad effects on tissues and endocrine systems that ultimately lead to the coordination of whole-body energy metabolism. Leptin seem to be involved in pregnancy, puberty, immune modulation, inflammation, wound healing and mutation. In coordination with mammary milk leptin, plasma leptin may act as an autocrine or paracrine signaling molecule on the mammary gland epithelial cell proliferation, differentiation, growth, apoptosis and function during early lactation period; by repartitioning of plasma nutrients towards milk secretion. It seems that the basal level of plasma leptin might be important for mammary gland to function normally and it might be involved in thermoregulation, satiation, endocrine homeostasis and systemic regulation in the neonate.
Keywords
Leptin; farm animal; reproduction; mammary function


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