Impact of the histological, biochemical, and cytogenetical changes caused by Ehrlich solid carcinoma (ESC) in the pregnant mice and treated with ethanolic extract of Tamarinds Indica seeds
Abd El-Aziz, Y., Rashed, M., Agamy, D., Elmalaky, H., Abo-Elhamd, R., Elsergany, M., Abdelhay, R., Abu Almaaty, A. (2023). Impact of the histological, biochemical, and cytogenetical changes caused by Ehrlich solid carcinoma (ESC) in the pregnant mice and treated with ethanolic extract of Tamarinds Indica seeds. EKB Journal Management System, 4(1), 84-95. doi: 10.21608/ajbas.2022.147856.1112
Yasmin M. Abd El-Aziz; Mariam Y. Rashed; Donia W. Agamy; Hend M. Elmalaky; Rahma D. Abo-Elhamd; Mariam M. Elsergany; Rahma M. Abdelhay; Ali Hussein Abu Almaaty. "Impact of the histological, biochemical, and cytogenetical changes caused by Ehrlich solid carcinoma (ESC) in the pregnant mice and treated with ethanolic extract of Tamarinds Indica seeds". EKB Journal Management System, 4, 1, 2023, 84-95. doi: 10.21608/ajbas.2022.147856.1112
Abd El-Aziz, Y., Rashed, M., Agamy, D., Elmalaky, H., Abo-Elhamd, R., Elsergany, M., Abdelhay, R., Abu Almaaty, A. (2023). 'Impact of the histological, biochemical, and cytogenetical changes caused by Ehrlich solid carcinoma (ESC) in the pregnant mice and treated with ethanolic extract of Tamarinds Indica seeds', EKB Journal Management System, 4(1), pp. 84-95. doi: 10.21608/ajbas.2022.147856.1112
Abd El-Aziz, Y., Rashed, M., Agamy, D., Elmalaky, H., Abo-Elhamd, R., Elsergany, M., Abdelhay, R., Abu Almaaty, A. Impact of the histological, biochemical, and cytogenetical changes caused by Ehrlich solid carcinoma (ESC) in the pregnant mice and treated with ethanolic extract of Tamarinds Indica seeds. EKB Journal Management System, 2023; 4(1): 84-95. doi: 10.21608/ajbas.2022.147856.1112

Impact of the histological, biochemical, and cytogenetical changes caused by Ehrlich solid carcinoma (ESC) in the pregnant mice and treated with ethanolic extract of Tamarinds Indica seeds

Alfarama Journal of Basic & Applied Sciences
Article 7, Volume 4, Issue 1, January 2023, Page 84-95  XML PDF (496.93 K)
Document Type: Original Article
DOI: 10.21608/ajbas.2022.147856.1112
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Authors
Yasmin M. Abd El-Aziz email 1; Mariam Y. Rashed2; Donia W. Agamy2; Hend M. Elmalaky2; Rahma D. Abo-Elhamd2; Mariam M. Elsergany2; Rahma M. Abdelhay2; Ali Hussein Abu Almaaty3
1Zoology Department, Faculty of Science, Port Said University, Port Said, Egypt.
2Zoology Department, Faculty of Science, Port-Said University, Egypt.
3Zoology Department, Faculty of Science, Port Said University
Abstract
All parts of Tamarinds indica plants are included in traditional medicine in India and other countries. There are many chemical values as phenolic materials that make it possess variable activities, most important of them antioxidant activity against cancer. The extract of Tamarinds Indica using to thwart various cancer types. Forty mice were divided into four groups; the first group was as control (normal mice), the second group was injected only with Ehrlich carcinoma cells, the third group was treated with Tamarinds indica extraction only, and the fourth group was injected with Ehrlich carcinoma cells and treated with Tamarinds indica extraction. At the final of the experiment, we represented the fourth group of mice has a significant reduction in cancer effects, which confirmed the anticancer activity of Tamarinds indica extraction in vivo (mice). Finally, the conclusion proves the efficacy of Tamarinds indica ethanolic extract as a cancer prophylactic chemotherapy in therapeutic approaches to treat cancer caused by Ehrlich cells in serum protein level, fetal tissues, cerebellum tissues, lung tissues, and chromosomes.
Keywords
Ehrlich cells; Tamarinds Indica; Mouse; Histology; Cytogentics
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