Assessment of Vitamin D Level and Nutritional Status in Children with Cholestatic Disorders | ||||
| The Egyptian Journal of Hospital Medicine | ||||
| Article 280, Volume 88, Issue 1, July 2022, Page 4009-4013 PDF (645.45 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ejhm.2022.254077 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Sarah Abdelrashid  ; Nehal El Koofy; Mona Fathy; Engy A. Mogahed; Rokaya Mohamed Elsayed
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| pediatric department, faculty of medicine, October 6 university, Cairo, Egypt | ||||
| Abstract | ||||
| Background: Malnutrition and vitamin D deficiency is a frequent complication in children with chronic cholestatic disorders. Objective: This study aimed to assess nutritional status and serum level of vitamin D in children with chronic cholestasis. Methods: Forty infants and children (1–6 years) with cholestatic liver diseases were enrolled from the Pediatric Hepatology Department, Cairo University Children’s Hospital. Nutritional history, anthropometric measurements [including weight, height, mid-upper arm circumference (MUAC) and triceps skin fold (TSF)] and serum vitamin D were assessed. Vitamin D was correlated with liver functions. Assessment of nutritional status was performed using subjective nutritional global assessment (SGA) and nutritional risk screening tool STRONGkids. Results: The mean age of the patients was 2.7 ± 1.67 and 67.5% were males. The most frequent diagnosis was biliary atresia (42.5%) followed by cholestasis with normal GGT (32.5%) then cholestasis with high GGT (25%). Although, all patients were on regular doses of oral vitamin D, the number of vitamin D deficient patients was 13 (32.5%). Vitamin D is not correlated with liver functions. Anthropometric measurements showed that TSF was the most accurate parameter to detect malnutrition (77.5% of patients were below fifth percentile). About 47 and 72 % of the patients had malnutrition according to SGA and STRONGKids respectively. Conclusion: Malnutrition and vitamin D deficiency are common among cholestatic children despite regular oral supplementations. MUAC and TSF are effective applied anthropometric measures for nutritional assessment. Vitamin D is not correlated to the liver functions. | ||||
| Keywords | ||||
| Anthropometry; Children; Cholestasis; Nutritional assessment; Vitamin D | ||||
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