TOXIC EFFECT OF HERBICIDE "MACHETE" ON THE HAEMATOLGICAL PICTURE AND SPLEENIC TISSUE IN RATS | ||||
Journal of Plant Protection and Pathology | ||||
Article 5, Volume 27, Issue 10, October 2002, Page 7033-7041 PDF (2.56 MB) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/jppp.2002.255168 | ||||
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Author | ||||
Fatma S. EI-Mahrouky | ||||
Plant Protection Research Institute, Agric. Res. Center, Dokki-Giza, Egypt | ||||
Abstract | ||||
The effect of 1/4 LDSO oral administration of herbicide "Machete" daily for S weeks on body weight and haematological parameters of albino rats including R.B.C.s, W.B.C.s, haemoglobin and packed cell volume were investigated. The herbicide caused a significant decrease in body weight and a slightly increase in W.B.C.s while red blood cells, haemoglobin and packed cells volume progressively insignificantly decreased. Histological Changes of spleens W8re shown in the form of lymphoid depletion and hyperplasia in the white pulps, while the red one and sinusoids were hyperemic. However, it was found that the use of sublethal doses of herbicides "Machete" has greatly affected the blood picture and spleen tissue of rats. | ||||
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