3-Aryl/hetaryl-2-cyanoacryloyl chlorides: Synthesis and Reactions with Binucleophiles Targeting Heterocycles
El-Helw, E., El-Ziaty, A., Ramadan, S. (2022). 3-Aryl/hetaryl-2-cyanoacryloyl chlorides: Synthesis and Reactions with Binucleophiles Targeting Heterocycles. EKB Journal Management System, 65(11), 565-572. doi: 10.21608/ejchem.2022.152901.6621
Eman A. E. El-Helw; Ahmed Kamel El-Ziaty; sayed Karam Ramadan. "3-Aryl/hetaryl-2-cyanoacryloyl chlorides: Synthesis and Reactions with Binucleophiles Targeting Heterocycles". EKB Journal Management System, 65, 11, 2022, 565-572. doi: 10.21608/ejchem.2022.152901.6621
El-Helw, E., El-Ziaty, A., Ramadan, S. (2022). '3-Aryl/hetaryl-2-cyanoacryloyl chlorides: Synthesis and Reactions with Binucleophiles Targeting Heterocycles', EKB Journal Management System, 65(11), pp. 565-572. doi: 10.21608/ejchem.2022.152901.6621
El-Helw, E., El-Ziaty, A., Ramadan, S. 3-Aryl/hetaryl-2-cyanoacryloyl chlorides: Synthesis and Reactions with Binucleophiles Targeting Heterocycles. EKB Journal Management System, 2022; 65(11): 565-572. doi: 10.21608/ejchem.2022.152901.6621

3-Aryl/hetaryl-2-cyanoacryloyl chlorides: Synthesis and Reactions with Binucleophiles Targeting Heterocycles

Egyptian Journal of Chemistry
Article 52, Volume 65, Issue 11, November 2022, Page 565-572  XML PDF (567.93 K)
Document Type: Review Articles
DOI: 10.21608/ejchem.2022.152901.6621
View on SCiNiTO View on SCiNiTO
Authors
Eman A. E. El-Helworcid 1; Ahmed Kamel El-Ziaty email orcid 2; sayed Karam Ramadan3
1Chemistry Department, Faculty of Science, Ain Shams University, Abassia, Cairo, Egypt
2Ain shams University
3chem.dept.asu
Abstract
In this review, we reported the synthetic method used to construct thirteen derivatives of 3-aryl/heteryl-2-cyanoacryloyl chloride followed by a focused survey on their spectral data and the synthetic importance of this scaffold for building a wide variety of heterocyclic skeletons using three different types of bidentate nucleophiles.
Keywords
Acryloyl chlorides; Activated nitrile; Bidentate Nucleophiles; Fused Heterocycles
Statistics
Article View: 153
PDF Download: 196