COMPARATIVE STUDY BETWEEN INTRAVENOUS LIDOCAINE AND DEXMEDETOMIDINE INFUSION FOR PREVENTION OF POSTOPERATIVE CATHETER-RELATED BLADDER DISCOMFORT - | ||||
ALEXMED ePosters | ||||
Article 3, Volume 4, Issue 3, September 2022, Page 26-27 | ||||
Document Type: Preliminary preprint short reports of original research | ||||
DOI: 10.21608/alexpo.2022.157782.1456 | ||||
View on SCiNiTO | ||||
Authors | ||||
Emad Abd-El Monem Areeda; Mounir Kamal Afify; Mohamed Mahmoud Abd El-Hady; Abdul-aziz Omar Abbas | ||||
Department of Anaesthesia and Surgical Intensive Care, Faculty of Medicine, University of Alexandria | ||||
Abstract | ||||
INTRODUCTION: Annually, about millions ofhospital admissionse.g., US receive urinary catheterization. Catheter is a tube system inserted/placed to the body for draining urine for therapeutic or diagnostic purposes, but might cause UTI or urethral scarring. CRBD: burning sensation, stabbing pain, urge to urinate, discomfort on suprapubic region after catheterization. The rate of CRBD ranges 47%-90%.Contributing factors; male sex, open surgeries, previous catheterization, age ˂50yrs. Pathogenesis: Activation of muscarinic receptors of cholinergic nerves, catheter triggering afferent nerves of the bladder resulting the release of Ach and involuntary contraction ofdetrusor muscles. Treatments; antimuscarinics, anaesthetics, antiepileptics, are frequently prescribed. IV dexmedetomidine: selective alpha2 adrenergic agonist with sedative, analgesics, antianxiety action without respiratory depression. It prevents CRBD by inhibiting M3 receptors. IV lidocaine has analgesic, anti-inflammatory and antihyperalgesic properties. Through analgesic and anti-inflammatory activities, itenhances postoperative recovery by opioid sparing and reducing immune alteration. It is assumed IV lidocaine has antimuscarinic properties. AIM OF THE WORK: The primary aim of the present work was to compare between intravenous lidocaine and dexmedetomidine infusion for prevention of postoperative catheter-related bladder discomfort (CRBD). The secondary aim was to study the effects of these drugs (intravenous dexmedetomidine and lidocaine) on; Intraoperative and postoperative hemodynamics, Postoperative analgesia and Sedation status of the patients. | ||||
Keywords | ||||
CATHETER-RELATED BLADDER DISCOMFORT; . IV dexmedetomidine; IV lidocaine | ||||
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